Description

Roxadustat is a potent oral hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor that stimulates erythropoiesis by stabilizing HIF, leading to increased endogenous erythropoietin production. It is widely researched for its potential in treating anemia associated with chronic kidney disease (CKD) and other hypoxia-related conditions.

This product contains 20mg roxadustat per capsule, provided in 3 capsules per box, designed for in vitro and in vivo research applications such as anemia models, oxygen sensing pathways, and metabolic regulation studies.

Manufactured by Jiangxi Shanxiang Pharmaceutical Co., Ltd. under Qingfeng Pharmaceutical Group, this product is approved by China’s NMPA under number H20249730 and product code 86905345000626.

?? Strictly for laboratory research use only. Not for human or veterinary use.

Product Specifications

Mechanism & Research Applications

Roxadustat inhibits HIF prolyl hydroxylase enzymes, preventing HIF degradation under normoxic conditions. Stabilized HIF activates transcription of genes involved in erythropoiesis and iron metabolism, resulting in increased production of endogenous erythropoietin and improved red blood cell formation.

This mechanism makes roxadustat a valuable compound for research on anemia of chronic kidney disease, hypoxia-related disorders, and oxygen sensing pathways.

Research applications include in vitro cell assays, animal models of anemia and hypoxia, gene expression studies related to HIF pathways, and metabolic regulation investigations.

Safety & Handling

• Use Restriction: For laboratory research only; not for clinical, diagnostic, or veterinary use.

• Protective Equipment: Use gloves, lab coat, and eye protection when handling.

• Storage: Keep sealed and stored below 25°C, away from moisture and direct sunlight.

• Disposal: Dispose of according to institutional and environmental safety protocols.

Research Use Disclaimer

This product is intended exclusively for laboratory research. It is not approved for therapeutic, diagnostic, or veterinary applications. Misuse may pose safety and legal risks. Always follow institutional biosafety and handling protocols.