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Sertraline Hydrochloride Capsules 50?mg Low price wholesale
$5.00
Sertraline Hydrochloride Capsules contain 50?mg of active SSRI compound per capsule. Each box includes 14 capsules × 3 blisters (42 capsules total). Manufactured by Sichuan Baicao Pharmaceutical Co., Ltd. and approved under NMPA H20070179, this product is suitable for laboratory research on depression, anxiety, and PTSD-related behavior models.?? Intended for laboratory research use only.?Please consult staff for other specifications and uses?
Description
Sertraline Hydrochloride is a selective serotonin reuptake inhibitor (SSRI) widely studied for its role in modulating serotonin levels in the brain. This product is designed for neuropharmacology, behavioral neuroscience, and psychotropic drug evaluation in laboratory environments.
Used extensively in preclinical models of major depressive disorder (MDD), generalized anxiety disorder (GAD), panic disorder, and post-traumatic stress disorder (PTSD), Sertraline offers consistent oral bioavailability and reliable CNS penetration, making it a preferred agent in mental health research.
Sertraline Hydrochloride Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Sertraline Hydrochloride Capsules |
| Generic Name | Sertraline HCl |
| CAS Number | 79559-97-0 |
| Molecular Formula | C17H17Cl2N•HCl |
| Molecular Weight | ~342.7?g/mol |
| Form | Capsule |
| Strength | 50?mg per capsule |
| Total Quantity | 42 capsules (14 × 3 blister packs) |
| Product Type | Oral capsule |
| Manufacturer | Sichuan Baicao Pharmaceutical Co., Ltd. |
| Approval Number | NMPA H20070179 (China) |
| Barcode | 6937152991884 |
| Storage | Store below 25?°C; keep dry and away from light |
| Intended Use | Research-only; not for clinical use |
Mechanism of Action
Sertraline selectively inhibits the reuptake of serotonin (5-HT) at the presynaptic neuronal membrane, enhancing serotonin levels in the synaptic cleft. It does not significantly affect norepinephrine or dopamine reuptake, making it a clean SSRI option in comparative drug models.
Research Applications
Depression Models: Widely used in chronic mild stress (CMS) models to reverse depressive behavior.
Anxiety & PTSD: Reduces startle response and increases exploratory behavior in rodent PTSD models.
Behavioral Pharmacology: Helps assess 5-HT receptor subtype interactions, SSRIs vs. SNRIs, and placebo control mechanisms.
Neuroendocrine Studies: Examines HPA axis modulation and cortisol suppression in stress response.
Safety & Handling Guidelines
Common lab observations: Mild sedation, weight variation, reduced food intake in rodent models.
Rare reactions: Seizure threshold alterations at very high doses.
Handling: Use PPE and sterile tools during capsule opening or compound extraction.
Storage: Dry, room temperature; avoid humidity and light exposure.
Research-Use Disclaimer
This product is supplied strictly for laboratory research use only. It is not for therapeutic, diagnostic, clinical, or veterinary use. Misuse of the product may pose serious health risks. Please handle with appropriate protective measures and comply with institutional biosafety regulations.
Additional information
| Weight | 1 kg |
|---|---|
| Dimensions | 28 × 26 × 28 cm |
Q1: What is Sertraline commonly used for in research?
A1: Sertraline is used to investigate antidepressant effects, neurochemical changes in serotonin signaling, and treatment of stress-related disorders.
Q2: Is this the same as clinical Zoloft®?
A2: Chemically, yes—it is the same active ingredient (Sertraline HCl), but this product is strictly for non-clinical, research use only.
Q3: Can this be used in animal models?
A3: Yes. It is widely used in rodents, zebrafish, and primate research models for mood, cognition, and SSRIs.
Q4: Is there documentation available?
A4: Yes, COA (Certificate of Analysis) and SDS (Safety Data Sheet) are available upon request.
Q5: Can you ship bulk quantities?
A5: Yes. We support wholesale, OEM, and global delivery. Contact us for bulk pricing.
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