Description
Sodium glucuronate is a sodium salt of D-glucuronic acid, a natural metabolite in phase II detoxification. It enhances hepatic clearance by conjugating toxins—forming water-soluble glucuronides—as well as supporting liver glycogen preservation and suppressing lipolysis. Injected in sterile form, it enables precise dosing in hepatoprotection, cirrhosis, and detox research models.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Sodium Glucuronate Injection (Dongfangming) |
| Generic Name | Sodium Glucuronic Acid (D-Glucuronic Acid, Sodium Salt) |
| CAS Number | 14984?34?0 |
| Molecular Formula | C?H??NaO? |
| Molecular Weight | ~234.25?g/mol |
| Dosage Form | Sterile aqueous injection |
| Strength per Vial | 0.133?g in 2?ml |
| Pack Size | 10 vials per box |
| Approval Number | H37023307 |
| Drug Standard Code | 86904083000219 |
| Manufacturer | Shandong Dongfangming Pharmaceutical Group Co., Ltd. |
| Barcode | 6935030530323 |
| Storage Conditions | Store below 25?°C, protected from light and moisture |
| Intended Use | Lab research: hepatoprotection, detoxification, liver injury models |
Mechanism of Action
Sodium glucuronate provides glucuronic acid that conjugates with toxins via glucuronidation, increasing their solubility and facilitating excretion through bile and urine. It also promotes liver glycogen storage and reduces lipid peroxidation, aiding in hepatoprotection and detox in preclinical models.
Research Applications
Acute and chronic hepatitis models
Prevention and reversal of liver fibrosis and cirrhosis
Toxic liver injury and oxidative stress studies
Enhancement of detoxification pathways via glucuronidation
Liver metabolic health and hepatocyte protection assays
Safety & Handling
Experimental Dose: Typically 0.133–0.266?g per injection in animal models, IM or IV, 1–2 times daily
Adverse Effects: None widely reported in lab settings
Contraindications: Hypersensitivity to glucuronates
Storage: Store sealed, below 25?°C, avoid light and humidity
Handling: Use lab PPE; maintain sterility
Core Keywords
sodium glucuronate injection, sodium glucuronic acid, CAS 14984?34?0, detox liver injection, hepatoprotection research, glucuronidation agent, H37023307, wholesale sodium glucuronate, lab-grade detox injection
Research Use Disclaimer
This product is intended exclusively for laboratory and preclinical research. It is not approved for clinical, therapeutic, diagnostic, or veterinary use. Misuse may entail legal or health risks. Use only under institutional protocols.


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