Description
Sodium valproate is widely used in neuroscience research to investigate antiepileptic mechanisms, neuroinflammation, and psychiatric disorder models. Its sustained-release formulation ensures prolonged plasma levels in experimental subjects, aiding long-duration pharmacokinetic and behavioral studies.
Sodium Valproate Sustained-release Tablets Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Sodium Valproate Sustained-release Tablets |
| Active Ingredient | Sodium Valproate (Valproic Acid Sodium Salt) |
| CAS Number | 1069-66-5 |
| Molecular Formula | C8H15NaO2 |
| Molecular Weight | 166.19 g/mol |
| Strength | 0.5g (500mg) per tablet |
| Formulation | Extended-release oral tablet |
| Pack Size | 30 tablets per bottle/box |
| Approval Number | HC20181023 (China NMPA) |
| Drug Code | 86979160000109 |
| Barcodes | 4711916012099 / 4711916015540 |
| Manufacturer | Synmosa Biopharma Corp. (Taiwan, China) |
| Storage Conditions | Store below 25°C, in dry environment |
| Research Use | Laboratory research only |
Sodium Valproate Sustained-release Tablets Mechanism of Action
Sodium valproate enhances GABAergic activity in the CNS by increasing GABA levels and inhibiting its breakdown. It also affects voltage-gated sodium channels and T-type calcium channels, reducing neuronal excitability—ideal for epilepsy and mood disorder model research.
Sodium Valproate Sustained-release Tablets Research Applications
Epilepsy Research Models
Effective in chemically and electrically induced seizure models; alters seizure threshold and frequency.Neuroprotective Studies
Investigated for antioxidant and anti-inflammatory roles in stroke, Alzheimer’s, and Parkinson’s models.Mood Disorders / Bipolar Disorder
Demonstrates mood-stabilizing effects; used in behavioral models of mania, depression, and aggression.PK/PD Studies
Excellent for pharmacokinetics profiling due to its slow, sustained-release characteristics.
Safety & Handling
Handling Guidelines: Wear gloves and avoid direct exposure. Follow biosafety practices.
Storage: Keep in original packaging at 15–25°C.
Shelf Life: 24–36 months from manufacturing date.
Toxicity: Use under controlled conditions. Inappropriate exposure may result in reproductive toxicity, hepatic stress, or CNS effects.
Research Use Disclaimer
This product is designated for scientific research purposes only. It is not authorized for use in humans, diagnostics, therapeutics, or veterinary applications. Misuse may pose health risks. Always follow local biosafety guidelines.


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