Sugammadex Sodium 200?mg/2?mL ×?10 Vials Wholesale price comparison
$2.00
Sugammadex sodium is a selective relaxant binding agent (SRBA) designed for rapid and safe reversal of neuromuscular blockade induced by steroidal muscle relaxants such as rocuronium and vecuronium. Each 2?mL vial contains 200?mg of sugammadex sodium. Manufactured by Guangdong Jiabo Pharmaceutical Co., Ltd., approval under NMPA H20223277, product code 86904948001252, barcode 6942746533371.
?? For laboratory research use only.?Please consult the staff for other purposes?
描述
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Sugammadex Sodium Injection (Rescue) |
| Generic Name | Sugammadex Sodium |
| CAS Number | 343306?79?6 fr.wikipedia.org+14en.wikipedia.org+14tcichemicals.com+14en.wikipedia.org+12medchemexpress.com+12pubchem.ncbi.nlm.nih.gov+12 |
| Molecular Formula | C??H???Na?O??S? |
| Molecular Weight | ~2,178?g/mol |
| Dosage Form | Sterile solution for intravenous injection |
| Strength | 100?mg/mL (200?mg per 2?mL vial) |
| Pack Size | 10 vials per box |
| Approval Number | H20223277 (China NMPA) |
| Product Code | 86904948001252 |
| Manufacturer | Guangdong Jiabo Pharmaceutical Co., Ltd. |
| Barcode | 6942746533371 |
| Storage | Store at 2–8?°C; protect from light |
| Intended Use | Laboratory research use only |
Mechanism of Action
Sugammadex is a modified ??cyclodextrin that rapidly encapsulates aminosteroid neuromuscular blocking agents like rocuronium and vecuronium, forming tight 1:1 complexes. This reduces free drug levels in plasma, prompting redistribution from neuromuscular junctions and thereby reversing paralysis—without the need for anticholinesterase agents.
Research Applications & Pharmacology
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Neuromuscular reversal models: Used in preclinical anesthesia to study reversal dynamics after rocuronium/vecuronium administration.
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Pharmacokinetics: Linear dose response (2–16 mg/kg), half-life ~2–2.5?hrs in normal renal function, >90% renal elimination .
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Pharmacodynamics: Provides faster recovery (T4/T1 >?0.9) than neostigmine, often within 2–3 minutes in studies .
Safety Profile & Handling
Common preclinical effects:
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Possible hypersensitivity/anaphylaxis on first or repeat dosing.
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Transient hypotension, cough, airway discomfort, or bradycardia.
Lab handling best practices:
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Administer IV slowly (?10?sec bolus).
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Monitor neuromuscular function and maintain ventilation.
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Use PPE and follow veterinary/human drug disposal procedures.
?? Research?Use Disclaimer
This product is intended exclusively for laboratory research. It is not approved for therapeutic, diagnostic, clinical, or veterinary applications. Misuse may present safety hazards and compromise experimental validity.
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 18 × 16 × 18 厘米 |
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