Sugammadex Sodium 200?mg/2?mL ×?10 Vials Wholesale price comparison

Sugammadex Sodium 200?mg/2?mL ×?10 Vials Wholesale price comparison

$2.00

Sugammadex sodium is a selective relaxant binding agent (SRBA) designed for rapid and safe reversal of neuromuscular blockade induced by steroidal muscle relaxants such as rocuronium and vecuronium. Each 2?mL vial contains 200?mg of sugammadex sodium. Manufactured by Guangdong Jiabo Pharmaceutical Co., Ltd., approval under NMPA H20223277, product code 86904948001252, barcode 6942746533371.
?? For laboratory research use only.?Please consult the staff for other purposes?

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Description

Product Specifications

AttributeDetails
Product NameSugammadex Sodium Injection (Rescue)
Generic NameSugammadex Sodium
CAS Number343306?79?6 fr.wikipedia.org+14en.wikipedia.org+14tcichemicals.com+14en.wikipedia.org+12medchemexpress.com+12pubchem.ncbi.nlm.nih.gov+12
Molecular FormulaC??H???Na?O??S?
Molecular Weight~2,178?g/mol
Dosage FormSterile solution for intravenous injection
Strength100?mg/mL (200?mg per 2?mL vial)
Pack Size10 vials per box
Approval NumberH20223277 (China NMPA)
Product Code86904948001252
ManufacturerGuangdong Jiabo Pharmaceutical Co., Ltd.
Barcode6942746533371
StorageStore at 2–8?°C; protect from light
Intended UseLaboratory research use only

Mechanism of Action

Sugammadex is a modified ??cyclodextrin that rapidly encapsulates aminosteroid neuromuscular blocking agents like rocuronium and vecuronium, forming tight 1:1 complexes. This reduces free drug levels in plasma, prompting redistribution from neuromuscular junctions and thereby reversing paralysis—without the need for anticholinesterase agents.


Research Applications & Pharmacology

  • Neuromuscular reversal models: Used in preclinical anesthesia to study reversal dynamics after rocuronium/vecuronium administration.

  • Pharmacokinetics: Linear dose response (2–16 mg/kg), half-life ~2–2.5?hrs in normal renal function, >90% renal elimination .

  • Pharmacodynamics: Provides faster recovery (T4/T1 >?0.9) than neostigmine, often within 2–3 minutes in studies .


Safety Profile & Handling

Common preclinical effects:

  • Possible hypersensitivity/anaphylaxis on first or repeat dosing.

  • Transient hypotension, cough, airway discomfort, or bradycardia.

Lab handling best practices:

  • Administer IV slowly (?10?sec bolus).

  • Monitor neuromuscular function and maintain ventilation.

  • Use PPE and follow veterinary/human drug disposal procedures.


?? Research?Use Disclaimer

This product is intended exclusively for laboratory research. It is not approved for therapeutic, diagnostic, clinical, or veterinary applications. Misuse may present safety hazards and compromise experimental validity.

Additional information

Weight1.1 kg
Dimensions18 × 16 × 18 cm

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