Description

Sugammadex is a modified ?-cyclodextrin derivative specifically developed to encapsulate and inactivate aminosteroid neuromuscular blocking agents such as rocuronium and vecuronium. It allows for the rapid reversal of muscle relaxation in surgical settings and is widely studied for mechanisms of neuromuscular pharmacology, drug-drug interaction modeling, and selective encapsulation chemistry.

This lyophilized formulation offers a stable research-grade form suitable for reconstitution in preclinical or in vitro research protocols.

Sugammadex Sodium Product Specifications

Sugammadex Sodium Mechanism of Action

Sugammadex works by forming a tight water-soluble complex with aminosteroid neuromuscular blocking agents (e.g., rocuronium, vecuronium), effectively removing them from circulation and reversing their pharmacologic activity. It does not interfere with acetylcholine metabolism, making it a unique tool in neuromuscular recovery and blockade reversal studies.

Sugammadex Sodium Research Applications

• Reversal of aminosteroid-induced neuromuscular blockade

• Cyclodextrin-based encapsulation chemistry

• Pharmacokinetics and drug interaction models

• Anesthetic recovery pathway modeling

• Biopharmaceutical formulation development

Safety & Handling Guidelines

• Observed Effects (in animal models): Bradycardia, hypersensitivity, hypotension

• Storage: Refrigerate if required by protocol; reconstitute with sterile water

• Handling: Use protective equipment; lab-grade use only

Research Use Disclaimer

This product is supplied exclusively for research purposes. Not intended for human, diagnostic, or therapeutic use. Misuse may lead to regulatory violations. Always follow institutional biosafety protocols and local legal requirements.