Tenofovir Alafenamide Fumarate Tablets (Meiganneng) – 25?mg × 30 Tablets
$2.00
Meiganneng Tenofovir Alafenamide Fumarate (TAF) tablets provide 25?mg per tablet, 30 tablets per bottle. Manufactured by Hunan Mingrui Pharmaceutical Co., Ltd., approved under H20213856. TAF is a liver-targeting nucleotide analog prodrug used in preclinical research for hepatitis B and HIV models, offering improved safety vs. older tenofovir forms.
?? For laboratory and research use only. Not for clinical applications.?Please consult staff for other specifications and uses?
描述
TAF is a potent nucleotide reverse transcriptase inhibitor delivering active tenofovir into hepatocytes and lymphocytes with minimal renal exposure, improving safety compared to Tenofovir Disoproxil Fumarate (TDF) . The fumarate salt enhances stability and tablet formulation performance .
Meiganneng tablets are formulated for research into antiviral efficacy, resistance development, metabolic processing, and comparative safety studies in HBV and HIV infection models.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Tenofovir Alafenamide Fumarate Tablets (Meiganneng) |
| Generic Name | Tenofovir Alafenamide Fumarate (TAF) |
| CAS Number | 1392275?56?7 |
| Molecular Formula | C??H??N?O?P·C?H?O? |
| Molecular Weight | ??1069?Da |
| Strength | 25?mg per tablet |
| Pack Size | 30 tablets per bottle |
| Dosage Form | Oral tablet |
| Approval Number | H20213856 (NMPA China) |
| Manufacturer | Hunan Mingrui Pharmaceutical Co., Ltd. |
| Barcode | 6920945600377 |
| Storage Conditions | Store ??25?°C, protected from moisture |
| Intended Use | Laboratory research: HBV & HIV antiviral studies, pharmacokinetics |
Mechanism of Action
TAF is a prodrug converted intracellularly to tenofovir diphosphate, which blocks viral reverse transcriptase, inhibiting viral replication. It has enhanced hepatic targeting and a better safety profile (lower renal/bone toxicity) versus TDF.
Research Applications
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HBV antiviral efficacy and resistance assays
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HIV preclinical replication and combination therapy research
-
Comparative pharmacokinetics vs. TDF
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Toxicology: bone and kidney safety in vitro/in vivo
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Mechanistic studies of nucleotide analog activation and metabolism
Safety & Handling
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For research purpose only—no clinical or veterinary use
-
Use with standard lab PPE (gloves, coat, goggles)
-
Store sealed, in a dry, cool environment (??25?°C)
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Dispose per institutional regulations
Core Keywords
tenofovir alafenamide fumarate, TAF 25?mg tablets, CAS 1392275?56?7, Meiganneng TAF, antiviral research compound, HBV HIV nucleotide RT inhibitor, laboratory tenofovir alafenamide
Research Use Disclaimer
This product is strictly for laboratory and preclinical research use. It is not approved for clinical, diagnostic, therapeutic, or veterinary applications. Improper use may result in health or regulatory consequences. Use only under appropriate protocols.
其他信息
| 重量 | 1 公斤 |
|---|---|
| 尺寸 | 23 × 26 × 23 厘米 |
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