Description
Tenofovir alafenamide (TAF) is a potent nucleotide reverse transcriptase inhibitor (NRTI) and prodrug of tenofovir. It is used in research models of chronic hepatitis B and HIV due to its ability to inhibit viral polymerase while offering improved renal and bone safety profiles relative to older formulations. This compact tablet form supports accurate dosing, compliance in animal models, and studies of antiviral efficacy and pharmacodynamics.
Tenofovir Alafenamide Fumarate Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Tenofovir Alafenamide Fumarate Tablets (Zhongyan) |
| Generic Name | Tenofovir Alafenamide Fumarate |
| CAS Number | 379270?37?8 |
| Molecular Formula | C??H??N?O?P |
| Molecular Weight | ~476.47?Da |
| Formulation | Film-coated oral tablet |
| Strength | 25?mg per tablet |
| Pack Size | 30 tablets per bottle |
| Dosage Form | Tablet |
| Approval Number | H20233581 |
| Drug Standard Code | 86900951000657 |
| Manufacturer | Tianjin Institute of Pharmaceutical Research Co., Ltd. |
| Barcode | 6927355700918 |
| Storage Conditions | Store below 25?°C, sealed in original container, protect from moisture/light |
| Intended Use | Laboratory and preclinical research use |
Tenofovir Alafenamide Fumarate Mechanism of Action
TAF acts as an NRTI by delivering tenofovir directly into infected cells, inhibiting HBV and HIV reverse transcriptase enzymes. It achieves high intracellular drug levels while maintaining lower systemic exposure and improved safety.
Tenofovir Alafenamide Fumarate Research Application Areas
Chronic hepatitis B virus suppression
HIV/HBV coinfection studies
Pharmacokinetic and pharmacodynamic evaluations
Resistance mutation and antiviral efficacy screening
Comparative toxicity and safety profiling
Safety & Handling
Handling: Laboratory PPE (gloves, coat, goggles) required.
Storage: Below 25?°C, dry, and shielded from light.
Precautions: Not for human or veterinary use; follow institutional biosafety guidelines.
Core Keywords
Tenofovir Alafenamide tablets, TAF 25mg Zhongyan, CAS 379270?37?8, HBV antiviral research, NRTI lab tablets, H20233581 tenofovir alafenamide, wholesale antiviral tablets, research-grade TAF tablets
Research Use Disclaimer
For preclinical and scientific research use only. Not for medical, clinical, diagnostic, or veterinary purposes. Misuse may carry regulatory, legal, or health risks. Use under approved institutional protocols only.


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