Tenofovir Amibufenamide Tablets 25?mg Low price wholesale
$2.00
Tenofovir Amibufenamide Tablets (Hengmu) contain 25?mg of tenofovir amibufenamide per film-coated tablet, packaged 28 tablets per box. Manufactured by Changzhou Hengbang Pharmaceutical Co., Ltd. (China). Approved under NMPA H20210029, this product is intended strictly for laboratory use in chronic hepatitis B (CHB) studies, viral replication inhibition, and pharmacokinetics modeling.
?? For research purposes only.?Please consult staff for other specifications and uses?
描述
Tenofovir Amibufenamide is a nucleotide analog reverse transcriptase inhibitor (NtRTI) prodrug, developed for its high liver-targeting efficiency and improved safety profile over traditional tenofovir-based agents. It is commonly studied in preclinical models of chronic hepatitis B virus (HBV) infection due to its potent suppression of viral DNA replication with lower systemic toxicity.
This formulation offers enhanced pharmacokinetic characteristics, better intracellular activation, and reduced renal and bone toxicity markers, making it ideal for comparative studies of antiviral drug development.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Tenofovir Amibufenamide Tablets (Hengmu) |
| Generic Name | Tenofovir Amibufenamide |
| Chemical Class | NtRTI (Nucleotide Reverse Transcriptase Inhibitor) |
| CAS Number | [To be verified; likely similar to Tenofovir-related compounds] |
| Molecular Formula | C21H28N5O6P (tentative) |
| Molecular Weight | ~ 477.45 g/mol |
| Strength | 25?mg per tablet |
| Quantity per Box | 28 tablets (film-coated) |
| Form | Oral tablets |
| Dosage Form | Tablet |
| Approval Number | H20210029 (China NMPA) |
| Product Code | 86983096000010 |
| Manufacturer | Changzhou Hengbang Pharmaceutical Co., Ltd. |
| Barcode | 6924647728315 |
| Storage | Store below 25?°C, keep in a dry place away from light |
| Intended Use | Laboratory research only |
Mechanism of Action
Tenofovir Amibufenamide is converted intracellularly into tenofovir diphosphate, which inhibits HBV reverse transcriptase by competing with natural substrates and causing DNA chain termination. It exhibits superior hepatic distribution and activation compared to traditional tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF).
Research Applications
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Chronic hepatitis B (CHB) suppression studies
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NtRTI comparative efficacy and toxicity models
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Hepatic targeting and drug activation pharmacokinetics
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In vitro HBV replication inhibition assays
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Resistance mutation screening in HBV reverse transcriptase
Safety & Handling
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Storage: Room temperature, sealed in original packaging
-
Handling: Use PPE; avoid inhalation or contact with skin and eyes
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Stability: Do not expose to heat or moisture
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Warning: Not for therapeutic or diagnostic use in humans or animals
Core Keywords
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Tenofovir Amibufenamide Tablets
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NtRTI hepatitis B research
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Tenofovir analog antiviral
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HBV replication inhibitors
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Tenofovir Amibufenamide 25mg Hengmu
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Nucleotide reverse transcriptase inhibitor
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Wholesale hepatitis B research drugs
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Laboratory grade tenofovir analog
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CHB antiviral compound
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Research use NtRTI tablets
Research Use Disclaimer
This product is intended strictly for laboratory research purposes only. It is not for human or animal consumption, nor for diagnostic or therapeutic use. Use only in accordance with appropriate safety protocols and institutional guidelines.
其他信息
| 重量 | 1 公斤 |
|---|---|
| 尺寸 | 26 × 23 × 26 厘米 |
A1: No. While both are tenofovir prodrugs and NtRTIs, they differ in molecular structure, pharmacokinetics, and activation pathways.
A2: The exact CAS number is under assignment or proprietary; it may differ from TAF (CAS 379270-37-8).
A3: No. It is strictly for in vitro or preclinical laboratory research. Not approved for clinical, veterinary, or diagnostic purposes.
A4: Yes. Certificate of Analysis (COA) and Safety Data Sheet (SDS) can be provided upon request.
A5: Yes. Bulk orders, OEM, and international B2B shipments are fully supported.
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