Description

Terlipressin acetate (CAS No. 914453-96-6) is a synthetic peptide and a vasopressin analogue recognized for its powerful vasoactive effects. As a highly selective vasopressin V1 receptor agonist, Terlipressin acetate reduces splanchnic blood flow and portal pressure, making it a valuable research tool for studying hemodynamic regulation and acute variceal bleeding.

Beyond its vasoactive action, Terlipressin acetate has shown promising anti-inflammatory and anti-oxidative properties, further extending its significance in experimental pharmacology. These properties highlight its potential for use in hepatorenal syndrome (HRS) research and investigations of norepinephrine-resistant septic shock.

Produced under strict GMP manufacturing conditions, Terlipressin acetate is supplied at high purity and stability, ensuring reliable performance in laboratory applications. With its well-documented pharmacological profile, it serves as an important compound for studies in vascular physiology, liver-related disorders, and systemic inflammation.

Applications in Research

• Exploration of portal hypertension and variceal bleeding mechanisms.

• Studies on renal perfusion and hepatorenal syndrome models.

• Investigations into inflammatory pathways and oxidative stress.

• Evaluation of alternative therapies for septic shock.

Wholesale & Retail Availability
Our Terlipressin acetate is available in both small laboratory-scale packaging and bulk wholesale quantities to meet the needs of research institutions, laboratories, and distributors worldwide.

Important Note: This product is strictly intended for laboratory research use only. It is not for human consumption, medical, or veterinary use.

Product Specifications

Mechanism of Action & Research Applications

Terlipressin acetate functions as a selective vasopressin V1 receptor agonist, leading to vasoconstriction of splanchnic circulation and a subsequent reduction in portal venous pressure. This makes it an essential compound for studying portal hypertension and variceal bleeding mechanisms.

In addition, Terlipressin acetate has been shown to enhance renal perfusion by increasing effective arterial blood volume, making it useful for research into hepatorenal syndrome (HRS). Its anti-inflammatory and anti-oxidative properties provide further opportunities for exploring systemic inflammation, oxidative stress, and shock models.

Research areas include:

• Acute variceal bleeding studies.

• Hepatorenal syndrome (HRS) pathophysiology.

• Sepsis and septic shock models.

• Vascular and inflammatory signaling pathways.

Development & Formulation Notes

Terlipressin acetate is a synthetic peptide analogue optimized for stability and selective receptor targeting. Manufactured under GMP standards, the peptide is lyophilized for long-term preservation and easy reconstitution. Batch testing ensures purity, potency, and reproducibility for laboratory experiments.

Packaging is designed to minimize peptide degradation and maintain stability during transport and storage. Each batch is fully traceable with quality documentation available upon request.

Logistics, Transport & Packaging

• Packaging: Supplied in sealed sterile vials, with multiple size options for retail and bulk orders.

• Transport: Shipped under controlled temperature conditions to maintain stability.

• Storage upon arrival: Recommended storage at -20°C. Avoid repeated freeze-thaw cycles.

• Wholesale & Retail Support: Available in laboratory research pack sizes and industrial bulk quantities.

Side Effects (For Research Reference Only)

• Vasoconstriction and hypertension

• Abdominal cramps or discomfort

• Decreased cardiac output (observed in experimental models)

• Electrolyte imbalance in extended studies

(All information provided is for research reference only. Not for human use.)

Disclaimer

Terlipressin acetate is provided exclusively for laboratory research purposes. It is not intended for human consumption, medical treatment, or diagnostic use. The purchaser must be qualified to handle laboratory chemicals and peptides safely.

Keywords

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