Description

Product Description

Tetrapeptide-4 is a synthetic bioactive peptide developed for cosmetic research applications focusing on anti-aging, wrinkle reduction, and skin resilience improvement. As a functional peptide compound, Tetrapeptide-4 plays a crucial role in restoring the structural integrity of the extracellular matrix (ECM), which is vital for maintaining firm and youthful-looking skin. In scientific studies, this tetrapeptide demonstrates an ability to upregulate the synthesis of key ECM components such as collagen types I and III, elastin, and fibronectin, thereby improving skin elasticity and reducing fine lines.

Tetrapeptide-4 acts as a signaling molecule that interacts with fibroblasts, stimulating their biosynthetic activity. This peptide’s mechanism helps restore the dermal matrix that becomes fragmented and weakened due to intrinsic aging and photoaging. As a result, Tetrapeptide-4 has become a valuable research compound for laboratories investigating novel anti-wrinkle formulations and regenerative cosmetic materials. Its high biocompatibility and molecular precision make it ideal for controlled formulation development.

In skin tissue models, Tetrapeptide-4 has shown significant anti-inflammatory properties, helping reduce oxidative stress markers that contribute to premature skin aging. It also strengthens the skin barrier by promoting lipid synthesis and supporting the integrity of dermal-epidermal junctions. Such multifunctional activity explains its inclusion in advanced peptide-based cosmetic systems designed for both preventive and corrective skin-aging studies.

Researchers investigating high-performance cosmetic peptides often use Tetrapeptide-4 alongside synergistic compounds such as Palmitoyl Tripeptide-1, Acetyl Hexapeptide-8, or Oligopeptide-1 to explore cumulative anti-aging effects. The combination of collagen-boosting and antioxidant mechanisms allows Tetrapeptide-4 to serve as an essential reference ingredient in formulation optimization studies for serums, emulsions, or nanoliposome delivery systems.

Tetrapeptide-4 is characterized by exceptional stability and solubility, ensuring compatibility with aqueous or mild emulsion-based research formulations. It provides researchers with a reliable bioactive model for studying peptide-based collagen induction and wrinkle reduction mechanisms at both the cellular and molecular levels.

Overall, Tetrapeptide-4 represents a modern scientific approach to skin rejuvenation research. Its biochemical precision and proven dermal-regenerative potential make it a vital peptide in laboratory studies investigating how targeted signaling sequences can reverse visible signs of aging and improve the biomechanical strength of the skin.

Product Specifications

Mechanism of Action

Tetrapeptide-4 functions primarily as a bio-signal modulator within the extracellular matrix of the skin. By activating dermal fibroblasts, it enhances their ability to produce structural proteins that reinforce the dermal network. The peptide’s activity includes upregulation of type I collagen, which forms the primary tensile framework of the skin, and type III collagen, which contributes to the skin’s flexibility and resilience. Additionally, Tetrapeptide-4 supports the assembly of fibronectin, an ECM glycoprotein responsible for anchoring cells to their structural surroundings.

At the cellular level, Tetrapeptide-4 modulates several key signaling pathways related to tissue regeneration, such as the TGF-β/SMAD and MAPK cascades. These pathways are essential for maintaining dermal homeostasis and promoting the synthesis of new connective tissue components. By influencing these mechanisms, Tetrapeptide-4 contributes to restoring youthful skin architecture and reducing the depth of wrinkles.

Moreover, Tetrapeptide-4 helps balance matrix metalloproteinase (MMP) activity, preventing excessive degradation of collagen fibers induced by UV radiation and oxidative stress. This dual action—stimulating new matrix synthesis while protecting existing ECM structures—makes Tetrapeptide-4 a uniquely versatile peptide in skin-aging research.

Tetrapeptide-4 also contributes to barrier repair and anti-inflammatory defense. Its activity can reduce cytokine-induced irritation, soothe the skin, and strengthen the lipid layer, which is crucial for maintaining moisture balance. In cosmetic research studies, formulations containing Tetrapeptide-4 have demonstrated improved skin density, elasticity, and texture after consistent exposure in vitro.

From a biochemical standpoint, Tetrapeptide-4’s structure allows efficient interaction with cell membrane receptors, ensuring rapid penetration and high bioavailability in dermal applications. This characteristic makes it suitable for investigating advanced delivery technologies, such as liposome encapsulation or polymer-based peptide stabilization systems, to enhance efficacy in experimental models.

The combined effects of collagen stimulation, antioxidant protection, and anti-inflammatory response position Tetrapeptide-4 as a cornerstone molecule in the ongoing exploration of cosmetic peptide-based dermal restoration.

Side Effects

In controlled laboratory settings, Tetrapeptide-4 has shown excellent biocompatibility and minimal cytotoxicity. Since it is a synthetic peptide designed to mimic naturally occurring amino acid sequences in human skin, it poses very low irritation potential in in vitro models. However, as with any peptide-based research material, it should be handled using proper laboratory safety protocols.

Researchers are advised to monitor for any signs of peptide instability under extreme pH or temperature conditions. Tetrapeptide-4 may degrade if exposed to prolonged high heat or direct UV light. In formulation testing, avoid using strong oxidants or high ionic strength buffers that could alter peptide conformation. No significant allergenic, mutagenic, or genotoxic responses have been reported in scientific literature.

All experimental applications should remain limited to controlled laboratory environments. This peptide is not intended for human or animal use, and all work involving Tetrapeptide-4 should follow institutional biosafety and chemical handling regulations.

Keywords

Tetrapeptide-4, cosmetic peptide, collagen synthesis, anti-aging peptide, skin-firming peptide, bioactive peptide, peptide supplier China, high purity tetrapeptide, peptide raw material manufacturer

Shipping Guarantee

All shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

Payment Support

We provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.

Disclaimer

All products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.