Description

Tofacitinib is a potent and selective inhibitor of Janus Kinases (JAK1 & JAK3, with some JAK2 activity). It disrupts the JAK–STAT signaling pathway, moderating cytokine-mediated immune responses. The Fufeng tablets deliver a consistent 5?mg dosage ideal for research involving immune modulation, inflammation, and signal transduction pathways.

Produced by Shandong Lukang Pharmaceutical Co., Ltd. and approved under NMPA registration number H20233995 with product code 86983198000093. Barcode is pending; you may contact our online pharmacist to submit.

?? This product is intended strictly for laboratory research use only. Not approved for clinical, therapeutic, or veterinary use.

Tofacitinib Citrate Tablets Product Specifications

Tofacitinib Citrate Tablets Mechanism & Research Applications

Tofacitinib competitively inhibits JAK1, JAK3 (and to some extent JAK2), blocking phosphorylation of STAT proteins and preventing cytokine signaling. This mechanism is highly useful in lab settings for:

• Immune modulation studies and cytokine response assays

• Inflammation and autoimmune preclinical models

• Comparative analysis with other JAK inhibitors

• Pharmacokinetic and pharmacodynamic profiling

• Signal transduction and gene expression research

Tofacitinib Citrate Tablets Side Effects (Research Model Observations)

Preclinical studies in vivo and in vitro have noted the following potential effects:

• Reduced white blood cell counts (lymphopenia, neutropenia)

• Elevated liver enzymes and altered lipid profiles

• Increased markers of infection and immune suppression

• Thrombosis indicators in high-risk or prolonged models

Researchers should implement appropriate monitoring protocols for immunosuppression, blood chemistry, and thrombotic risk in experimental models.

Safety & Handling

• Usage Restriction: Laboratory research only. Not approved for clinical or veterinary use

• Personal Protection: Use laboratory PPE including gloves, goggles, and lab coats

• Storage: Keep sealed at 20–25?°C, protected from light

• Disposal: Dispose of remaining material per institutional chemical safety protocols

Core Keywords

Tofacitinib citrate tablets, Fufeng tofacitinib, JAK inhibitor 5?mg tablet, research-grade tofacitinib, immune modulation compound, NMPA H20233995 tofacitinib, Shandong Lukang tofacitinib, lab-use signal transduction drug, wholesale tofacitinib tablets

Research Use Disclaimer

This product is exclusively for laboratory research use and is not approved for therapeutic, diagnostic, clinical, or veterinary purposes. Misuse may lead to health or regulatory risks. Always adhere to institutional safety and handling protocols.