Tofacitinib Citrate Tablets (Jiudian) 5?mg – Low price wholesale comparison

描述

Tofacitinib is a selective inhibitor of JAK1 and JAK3 enzymes, disrupting the JAK-STAT pathway and modulating cytokine-driven immune responses. The Jiudian formulation delivers 5?mg per tablet, suitable for preclinical and pharmacological research in areas such as inflammation, autoimmunity, and cell signaling.

Manufactured by Hunan Jiudian Pharmaceutical Co., Ltd., approved under China NMPA registration number H20233220, with product code 86981741000019. Barcode is pending; please contact our online pharmacist for submission.

?? This product is strictly for laboratory research use only. Not approved for clinical, therapeutic, or veterinary applications.

Product Specifications

Mechanism & Research Applications

Tofacitinib competitively inhibits JAK1 and JAK3 (and to a lesser extent JAK2), blocking STAT activation and interrupting cytokine-mediated signaling pathways. It’s widely used in lab settings for:

• Immune signaling and cytokine modulation studies

• Autoimmune inflammation and disease models

• Comparative testing with other JAK inhibitors

• Pharmacokinetic/pharmacodynamic profiling

• Cell signaling and transcription regulation research

Side Effects (Research Model Observations)

Preclinical and lab studies have reported potential side effects including:

• Decreased white blood cells (lymphopenia/neutropenia)

• Elevated liver enzyme levels

• Increased risk of infection markers and immunosuppression

• Altered lipid metabolism and blood pressure changes

Safety & Handling

• Use Restriction: For laboratory research only; not approved for clinical, diagnostic, or veterinary use

• Handling: Use PPE—gloves, lab coat, and eye protection

• Storage: Keep sealed, 20–25?°C, avoid heat and light exposure

• Disposal: Follow institutional protocols for pharmaceutical waste

Core Keywords

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Research Use Disclaimer

This product is strictly for laboratory research purposes. It is not approved for therapeutic, diagnostic, clinical, or veterinary use. Misuse may pose health or legal risks. Always adhere to institutional and national biosafety standards.