描述
Tolvaptan is a selective vasopressin V2-receptor antagonist widely used in biomedical research, particularly in studies on autosomal dominant polycystic kidney disease (ADPKD) and electrolyte imbalance. It promotes water excretion (aquaresis) without significant sodium loss, making it a key tool in renal and endocrinology research.
This product delivers 15mg of tolvaptan per tablet, supplied in a box of 8 tablets, and is manufactured by Chengdu Better Pharmaceutical Co., Ltd., with NMPA approval number H20233073.
Note: This item is for laboratory research use only and is not intended for human or veterinary use.
Product Specifications
Parameter | Details |
---|---|
Product Name | Tolvaptan Tablets (Better) |
Generic Name | Tolvaptan |
CAS Number | 150683-30-0 |
Molecular Formula | C26H25ClN2O3 |
Molecular Weight | 448.94 g/mol |
Dosage Form | Tablet |
Strength | 15mg per tablet |
Quantity | 8 tablets per box |
Approval Number | H20233073 (China NMPA) |
Product Code | 86902013001411 |
Manufacturer | Chengdu Better Pharmaceutical Co., Ltd. |
Barcode | 6923528100332 |
Intended Use | Laboratory research only |
Storage Conditions | Store below 25°C, dry, and protected from light and moisture |
Mechanism of Action & Research Applications
Tolvaptan inhibits the vasopressin V2 receptor in the kidney’s collecting ducts, thereby reducing water reabsorption and increasing free water excretion. This mechanism is essential for:
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ADPKD pathogenesis research
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Investigating water-electrolyte balance
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Evaluating vasopressin signaling pathways
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Modeling hyponatremia in experimental systems
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Studying diuretic effects without natriuresis
Known Side Effects in Research Contexts
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Polyuria
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Increased thirst
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Elevated liver enzymes
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Fatigue
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Headache
Handling & Safety Information
Use Restriction: For research use only, not for clinical, diagnostic, or therapeutic use.
Personal Protection: Wear gloves, lab coat, and protective eyewear.
Storage: Store below 25°C in a dry, light-resistant environment.
Disposal: Dispose of according to institutional and national chemical waste guidelines.
Research Use Disclaimer
This product is intended exclusively for laboratory research purposes. It is not intended for human or veterinary use, therapeutic applications, or diagnostic testing. Always follow institutional safety protocols when handling.
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