Toremifene Citrate Tablets (Tianheng/Shurui) – 60?mg

Toremifene Citrate Tablets (Tianheng/Shurui) – 60?mg

$1.00

Toremifene citrate (Tianheng/Shurui) is a selective estrogen receptor modulator (SERM) used in experimental research on hormone receptor pathways. Approved in China (NMPA H20061284; Code?86904561000595) and manufactured by Ningbo Tianheng Pharmaceutical Co., Ltd. Supplied as 60?mg tablets (30 tablets per box, barcode 6944580400383). Strictly for laboratory research only

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描述

Toremifene Citrate Product Specifications

Attribute Details
Product Name Toremifene Citrate Tablets (Tianheng/Shurui)
Strength 60?mg per tablet
Quantity 30 tablets per box
Dosage Form Oral tablet
Approval Number China NMPA H20061284
Product Code 86904561000595
Barcode 6944580400383
Manufacturer Ningbo Tianheng Pharmaceutical Co., Ltd.
CAS Number 89778?26?7 (citrate: 89778?27?8) goodrx.com+14en.wikipedia.org+14tajlifesciences.com+14
Molecular Formula C??H??ClNO? (toremifene citrate)
Molecular Weight ~602?g/mol (citrate salt)
Intended Use Laboratory research only — Not for clinical or veterinary use

Toremifene Citrate Mechanism of Action

Toremifene is a SERM that binds estrogen receptors, acting as an antagonist in breast tissue and agonist in bones and liver. It inhibits estrogen-driven cancer cell growth and modulates bone/lipid metabolism drugs.com+1cancer.gov+1.


Research & Pharmacology Context

  • FDA-approved for metastatic estrogen-receptor–positive breast cancer

  • Features:

    • Oral bioavailability ~100%

    • Elimination half-life: 3–7 days; active metabolites persist 4–21 days

    • Metabolized by CYP3A4 with QT interval prolongation and drug interaction risk


 Research Applications

  • Estrogen receptor signaling and cancer cell growth studies

  • Bone metabolism and density research

  • Drug-drug interaction testing (CYP3A4 substrates/inhibitors)

  • QT interval or cardiac safety assays

  • Lipid metabolism model investigations


?? Research?Use Only Disclaimer

This product is provided strictly for laboratory research and development use only. Not intended for clinical, veterinary, diagnostic, or therapeutic applications.

其他信息

重量 1.1 公斤
尺寸 18 × 16 × 18 厘米

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Can I use this product for patients?

No. It is strictly for laboratory research, not for clinical, diagnostic, therapeutic, or veterinary applications.

How does Toremifene work?

It binds estrogen receptors; it antagonizes breast tissue (blocking estrogen) and agonizes bone/liver, altering gene expression and growth signaling

What are its common research usages?

It’s used in ER+ breast cancer models, bone density and metabolism assays, drug interaction studies, cardiac safety (QT prolongation), and lipid profile research.

What precautions should I take during experiments?

Handle with proper lab PPE in compliance with cytotoxic and hormonal agent protocols. Monitor storage (<25°C), and avoid contamination with CYP3A4 inhibitors. Dispose of waste properly per institutional regulations.

Are COA/SDS documents available?

Yes — COA and SDS are available upon request for qualified research institutions.


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