描述
Toremifene Citrate Product Specifications
Attribute | Details |
---|---|
Product Name | Toremifene Citrate Tablets (Tianheng/Shurui) |
Strength | 60?mg per tablet |
Quantity | 30 tablets per box |
Dosage Form | Oral tablet |
Approval Number | China NMPA H20061284 |
Product Code | 86904561000595 |
Barcode | 6944580400383 |
Manufacturer | Ningbo Tianheng Pharmaceutical Co., Ltd. |
CAS Number | 89778?26?7 (citrate: 89778?27?8) goodrx.com+14en.wikipedia.org+14tajlifesciences.com+14 |
Molecular Formula | C??H??ClNO? (toremifene citrate) |
Molecular Weight | ~602?g/mol (citrate salt) |
Intended Use | Laboratory research only — Not for clinical or veterinary use |
Toremifene Citrate Mechanism of Action
Toremifene is a SERM that binds estrogen receptors, acting as an antagonist in breast tissue and agonist in bones and liver. It inhibits estrogen-driven cancer cell growth and modulates bone/lipid metabolism drugs.com+1cancer.gov+1.
Research & Pharmacology Context
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FDA-approved for metastatic estrogen-receptor–positive breast cancer
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Features:
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Oral bioavailability ~100%
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Elimination half-life: 3–7 days; active metabolites persist 4–21 days
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Metabolized by CYP3A4 with QT interval prolongation and drug interaction risk
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Research Applications
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Estrogen receptor signaling and cancer cell growth studies
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Bone metabolism and density research
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Drug-drug interaction testing (CYP3A4 substrates/inhibitors)
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QT interval or cardiac safety assays
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Lipid metabolism model investigations
?? Research?Use Only Disclaimer
This product is provided strictly for laboratory research and development use only. Not intended for clinical, veterinary, diagnostic, or therapeutic applications.
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