描述
Toremifene Citrate Product Specifications
Attribute | Details |
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Product Name | Toremifene Citrate Tablets (Ovry®) |
Strength | 60?mg per tablet |
Quantity | 10 tablets per blister × 3 blisters = 30 tablets per box |
Dosage Form | Oral tablet |
Approval No. | China NMPA?H20243050 |
Product Code | 86901425001187 |
Barcode | 6953272600284 |
Manufacturer | Jiangsu Ascend Pharmaceutical Co., Ltd. |
Intended Use | Laboratory research use only — Not for human use |
Mechanism of Action
Toremifene is a SERM that functions as an estrogen receptor antagonist in breast tissue, while having partial estrogenic effects in bones and lipid metabolism. It is widely used as a reference compound in estrogen-receptor assays and breast cancer model systems.
Research & Reference Data
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Clinically approved for metastatic estrogen-receptor–positive breast cancer in post-menopausal women, at a dose of 60?mg once daily.
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Pharmacokinetics: nearly 100% oral bioavailability, half-life of 3–7 days, high protein binding (~99.7%). en.wikipedia.org
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Known to prolong QT interval; commonly used in studies evaluating cardiac safety and receptor interactions. pubchem.ncbi.nlm.nih.gov+9dailymed.nlm.nih.gov+9dailymed.nlm.nih.gov+9
Research Applications
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ER+ breast cancer cell models
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Receptor binding and signaling assays
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SERM comparative pharmacology
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QT prolongation modeling and toxicity screening
?? Disclaimer
This product is provided strictly for laboratory research and development use only.
mood –
The package is damaged, you need to resend it to me, thank you