Description
Trazodone is a Serotonin Antagonist and Reuptake Inhibitor (SARI) used extensively as an antidepressant, anxiolytic, and hypnotic behavior modulator in neuroscience studies. It selectively inhibits serotonin reuptake and antagonizes 5?HT?A, histamine H?, and ???adrenergic receptors.
Widely used in rodent models to study depression, anxiety, insomnia, memory, and receptor pharmacotherapy, trazodone offers a complex neurochemical profile ideal for detailed neuropsychopharmacology exploration.
Trazodone Hydrochloride Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Trazodone Hydrochloride Tablets (Anshi) |
| Generic Name | Trazodone HCl |
| CAS Number | 25332?39?2 |
| Molecular Formula | C??H??ClN?O·HCl |
| Molecular Weight | 408.32?g/mol |
| Formulation | Film-coated oral tablets |
| Strength | 25?mg per tablet |
| Pack Size | 20 tablets × 5 blisters = 100 tablets |
| Dosage Form | Tablet |
| Approval No. | NMPA?H20060037 |
| Product Code | 86901287000137 |
| Manufacturer | Shenyang Funing Pharmaceutical Co., Ltd. |
| EAN Barcode | 6938438200089 |
| Storage Conditions | Store in a cool, dry place below 25?°C |
| Intended Use | Laboratory research use only |
Trazodone Hydrochloride Mechanism of Action
Trazodone functions by blocking serotonin reuptake, antagonizing 5?HT?A, ??-adrenergic, and histamine H? receptors . This combination promotes mood stabilization, anxiolytic effects, and sleep induction—making it highly versatile for behavioral and CNS pharmacology research.
Research Applications
Preclinical depression/anxiety models: Evaluates antidepressant and anxiolytic effects.
Insomnia and sleep studies: Assesses sleep architecture and latency improvements.
Neurotransmission analysis: Examines serotonin, noradrenaline, and histamine pathway interactions.
Cognitive & memory behavior: Used in rodent paradigms of memory and synaptic plasticity.
Drug-comparison studies: Ideal for comparing trazodone against SSRIs, SNRIs, and atypical antipsychotics.
Safety & Handling
Common lab effects: Drowsiness, dry mouth, mild hypotension – reflecting clinical pharmacology .
Handling: Wear PPE; handle under lab safety protocols.
Storage: Keep sealed in original packaging, away from heat and moisture.
Research-Use Disclaimer
This product is strictly for laboratory research use only. It is not approved for clinical, diagnostic, therapeutic, or veterinary use. Improper or unauthorized use may pose health risks. Please follow institutional biosafety protocols accurately.


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