Description
Trimebutine Maleate Tablets Product Specifications
| Specification | Description |
|---|---|
| Product Name | Trimebutine Maleate Tablets (Renhe / Shuangdi) |
| Generic Name | Trimebutine Maleate |
| CAS Number | 34140?59?5 |
| Molecular Formula | C??H??NO? · C?H?O? |
| Molecular Weight | 503.54?g/mol |
| Formulation | Oral film-coated tablet |
| Strength | 100?mg (as maleate salt) per tablet |
| Pack Size | 2 × 14 tablets per box |
| Approval Number | H20010696 (NMPA, China) |
| Product Code | 86902928000110 |
| Manufacturer | Shanxi Shuangyan Pharmaceutical Co., Ltd. |
| Barcode | 6970045662362 |
| Storage Conditions | Store below 30?°C in a dry, ventilated place away from light |
| Intended Use | For laboratory research only |
Trimebutine Maleate Tablets Mechanism of Action
Trimebutine is a multimodal GI spasmolytic:
Antimuscarinic action on smooth muscle receptors
Weak ?-opioid and ?/? receptor agonist activity
Inhibition of L?type calcium channels and calcium-dependent potassium channels to regulate intestinal contractility drugs.ncats.io+2en.wikipedia.org+2go.drugbank.com+2
Research Applications & Pharmacology
Gastrointestinal motility models: both stimulant and relaxant effects are concentration-dependent
Irritable Bowel Syndrome (IBS): widely used in in vivo and in vitro IBS studies
Smooth muscle and spasm testing: modulation of intestinal phase III in migrating motor complex
Cell channel research: calcium and potassium channel inhibition assays
Pain and opioid pathway research: useful for exploring mild ?-opioid mediated analgesia
Safety Profile & Handling
Preclinical safety: low incidence of toxicity; mild sedation and GI effects at higher dosing
Laboratory precautions: use PPE—gloves, mask, lab coat; avoid inhalation or ingestion
Storage: store under recommended conditions, shielded from humidity
Disposal: follow institutional chemical waste disposal guidelines
Core Keywords
trimebutine maleate, GI spasmolytic research, antimuscarinic agent, CAS?34140?59?5, IBS research chemical, calcium channel inhibitor, opioid agonist GI, Renhe Shuangdi trimebutine, wholesale trimebutine tablets
Research?Use Disclaimer
This product is intended exclusively for laboratory research. It is not approved for clinical, diagnostic, therapeutic, or veterinary use. Misuse may pose health risks. Always comply with institutional and safety protocols.


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