Description

Product Description

Tripeptide-10 is a short-chain synthetic peptide designed to mimic endogenous signaling peptides within the dermal extracellular matrix. Its sequence facilitates targeted interaction with fibroblasts, regulating collagen and elastin synthesis, extracellular matrix remodeling, and overall dermal integrity. This peptide is utilized extensively in experimental models to study anti-aging effects, wrinkle reduction, and skin regeneration pathways.

Molecular Function and Bioactivity
Tripeptide-10 functions as a signaling molecule within dermal fibroblasts. It enhances transcription of collagen types I and III and stimulates elastin and fibronectin synthesis. Its amphiphilic nature allows interaction with lipid bilayers, promoting penetration into the dermis, which is essential for laboratory research involving topical peptide delivery systems.

Fibroblast Modulation
Experimental studies demonstrate that Tripeptide-10 activates fibroblasts, stimulating proliferation, migration, and extracellular matrix deposition. These effects lead to measurable increases in dermal density, firmness, and elasticity in vitro. The peptide’s ability to regulate fibroblast behavior is critical for research on collagen remodeling, wrinkle attenuation, and skin rejuvenation.

Extracellular Matrix Preservation
Tripeptide-10 suppresses matrix metalloproteinases (MMP-1 and MMP-9), enzymes responsible for degrading dermal collagen and elastin. By inhibiting these MMPs, the peptide maintains extracellular matrix integrity, making it a powerful tool for laboratory studies on skin aging and anti-wrinkle interventions.

Synergistic Research Applications
Tripeptide-10 is often combined with other bioactive peptides such as palmitoyl tripeptides and acetyl hexapeptides to assess synergistic effects on collagen synthesis, dermal elasticity, and fibroblast activity. This combinatorial approach enables laboratory researchers to design multi-targeted anti-aging peptide formulations.

Stability and Handling
Supplied as a lyophilized powder with ≥99% purity, Tripeptide-10 is soluble in water and aqueous buffers, suitable for various laboratory research applications. Stability is maintained under recommended storage conditions (2–8 °C) and protected from light and moisture. Proper handling ensures consistent experimental reproducibility and minimizes peptide degradation.

Laboratory Research Applications
Tripeptide-10 is used in:

• Human dermal fibroblast cultures

• Reconstructed human epidermal models

• Collagen and elastin synthesis assays

• Matrix metalloproteinase activity analysis

• Fibroblast proliferation and migration studies

These studies provide critical insights into peptide bioactivity, dermal regeneration pathways, and the development of experimental cosmetic formulations.

Product Specifications

Mechanism of Action

Tripeptide-10 exerts its anti-wrinkle and skin regeneration effects through fibroblast activation, extracellular matrix protein synthesis, and MMP inhibition.

1. Collagen Stimulation
   Upregulates TGF-β signaling, enhancing collagen I and III synthesis to strengthen dermal architecture, improve elasticity, and reduce wrinkles.

2. Elastin Production
   Stimulates elastin synthesis, contributing to dermal flexibility and resilience.

3. Matrix Metalloproteinase Inhibition
   Suppresses MMP-1 and MMP-9 activity, preventing degradation of collagen and elastin.

4. Fibroblast Activation
   Promotes fibroblast proliferation and migration, supporting extracellular matrix deposition and tissue repair.

5. Anti-Inflammatory Modulation
   Reduces IL-6, TNF-α, and COX-2 expression, minimizing inflammatory stress in dermal models.

6. Synergistic Peptide Applications
   Enhances the effects of other peptides when studied in combination, improving collagen synthesis, dermal integrity, and anti-wrinkle outcomes in experimental research.

   

Side Effects

Tripeptide-10 is intended solely for laboratory research use. Observed outcomes in vitro demonstrate minimal cytotoxicity. Considerations include:

• Concentration-dependent cytotoxicity; perform preliminary assays before extensive studies.

• Solvent compatibility; use water or aqueous buffers.

• Store at 2–8 °C, protected from light and moisture.

• Use standard laboratory PPE.

• Not intended for human or veterinary administration.

• Stable for ≥24 months under recommended storage conditions.

Keywords

Tripeptide-10, anti-wrinkle peptide, cosmetic peptide, skin aging research, collagen stimulator, fibroblast regulator, laboratory research peptide, high-purity peptide, peptide wholesale China, OEM peptide production, China peptide manufacturer

Shipping Guarantee

All Tripeptide-10 shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We Tripeptide-10 ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

Payment Support

We Tripeptide-10 provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.

Disclaimer

All Tripeptide-10 products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.