Description

Urapidil Hydrochloride is an antihypertensive compound used in laboratory studies for its dual mechanism as an ?1-adrenergic receptor antagonist and central serotonin (5-HT1A) agonist. It is widely applied in cardiovascular and hemodynamic research for its ability to lower blood pressure without reflex tachycardia.

Each ampoule contains 25mg of Urapidil Hydrochloride in 5ml, with 5 ampoules per box. This research-grade injectable formulation is produced by Hebei Yipin Pharmaceutical Co., Ltd., and approved by the China NMPA under registration number H20123353, product code 86909649000016.

For research use only. Not approved for human or veterinary applications.

Product Specifications

Mechanism & Research Applications

Urapidil works by blocking ?1-adrenergic receptors, causing vasodilation and reduced peripheral resistance. It also activates 5-HT1A receptors centrally, further aiding in blood pressure reduction without triggering reflex tachycardia—making it ideal for modeling controlled antihypertensive effects.

Research applications include:

• Experimental models of essential and resistant hypertension

• Vasodilation and vascular reactivity studies

• Autonomic nervous system modulation

• Investigations into 5-HT1A agonist mechanisms

• Combination studies with ?-blockers and ACE inhibitors

Safety & Handling

• Use Restriction: For research use only. Not for human or veterinary application.

• PPE Required: Wear gloves, lab coat, and protective eyewear during handling.

• Storage: Keep sealed below 25°C. Avoid moisture and direct sunlight.

• Disposal: Dispose in accordance with local regulations for chemical waste.

Research Use Disclaimer

This product is intended strictly for laboratory research use. It is not certified for clinical, diagnostic, or veterinary applications. Improper handling or misuse may pose health or legal risks. Always comply with relevant biosafety and institutional guidelines.