Vardenafil Hydrochloride Tablets – Wei?Er?Ting 20?mg ×?4 Tablets
$1.00
Vardenafil is a potent and selective phosphodiesterase?5 (PDE5) inhibitor widely used in cardiovascular and erectile dysfunction research. These 20?mg film-coated tablets (4 per blister pack) by Anhui Pioneer Pharmaceutical are for laboratory and preclinical research only. Not approved for clinical, diagnostic, therapeutic, or veterinary use.?Please consult staff for other specifications and uses?
描述
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Vardenafil Hydrochloride Tablets (Wei?Er?Ting®) |
| Generic Name | Vardenafil Hydrochloride |
| CAS Number | 224785?90?4 (base) / 330808?88?3 (HCl trihydrate) chemicalbook.com+14go.drugbank.com+14medchemexpress.com+14 |
| Molecular Formula | C??H??N?O?S · HCl · 3H?O (trihydrate) |
| Molecular Weight | ~579.1?g/mol |
| Dosage Form | Film-coated oral tablet |
| Strength | 20?mg per tablet |
| Pack Size | 4 tablets per box |
| Approval Number | China NMPA H20244792 |
| Product Code | 86904339000956 |
| Manufacturer | Anhui Pioneer Pharmaceutical Co., Ltd. |
| Barcode | 6953780000415 |
| Storage Conditions | Store at 15–25?°C; protect from light and moisture |
| Intended Use | Laboratory/preclinical research only |
Mechanism of Action
Vardenafil inhibits PDE5 selectively, preventing cGMP breakdown and enhancing NO-mediated smooth muscle relaxation in penile corpora cavernosa and vasculature.
Research Applications & Pharmacology
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Erectile Dysfunction (ED) & Andrology Models: Extensively utilized to study sexual function, vascular physiology, and smooth muscle mechanisms .
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Cardiovascular & Pulmonary Research: Used to investigate vasodilatory responses and pulmonary hypertension models.
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Comparative Analysis: Demonstrates higher potency (~0.7?nM IC?? for PDE5) and selectivity over sildenafil and tadalafil .
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Pharmacokinetics: Oral bioavailability ~15%, protein binding ~95%, hepatic metabolism via CYP3A4, half-life 4–5 hours en.wikipedia.org+1ru.wikipedia.org+1.
Safety Profile & Handling
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Adverse Effects: Headache, flushing, nasal congestion, back pain, dizziness; rare hypotension, QT prolongation .
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Drug Interactions & Contraindications: Avoid use with nitrates, alpha-blockers, or CYP3A4 inhibitors in in vivo studies; monitor cardiovascular parameters .
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Handling Instructions: Use PPE, store under recommended conditions, discard expired tablets per lab protocols.
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Lab Safety: Not for human/animal administration; research-only. Discard per institutional biosafety guidelines.
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 18 × 16 × 18 厘米 |
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