Vardenafil Hydrochloride Tablets 20?mg Wholesale price comparison
$2.00
Vardenafil is a powerful, selective phosphodiesterase?5 (PDE5) inhibitor widely used in erectile dysfunction and vascular research. This product is supplied as 5 tablets (20?mg each) by Anhui Pioneer Pharmaceutical Co., intended exclusively for laboratory and preclinical research. Not approved for clinical, diagnostic, therapeutic, or veterinary use.?Please consult staff for other specifications and uses?
描述
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Vardenafil Hydrochloride Tablets (Guan’ai® / Qing Doctor) |
| Generic Name | Vardenafil Hydrochloride |
| CAS Number | 224785?90?4 (free base) / 330808?88?3 (HCl trihydrate) access.portico.org+12en.wikipedia.org+12accessdata.fda.gov+12 |
| Molecular Formula | C??H??N?O?S · HCl · 3H?O (trihydrate) |
| Molecular Weight | ~579.1?g/mol (trihydrate) |
| Dosage Form | Film-coated oral tablet |
| Strength | 20?mg per tablet |
| Pack Size | 5 tablets per box (1 blister pack) |
| Approval No. | China NMPA H20244792 |
| Product Code | 86904339000956 |
| Manufacturer | Anhui Pioneer Pharmaceutical Co., Ltd. |
| Barcode | 6953780000446 |
| Storage | Store at 15–25?°C; protect from light and moisture |
| Intended Use | Laboratory/preclinical research only |
Mechanism of Action
Vardenafil selectively inhibits PDE5, preventing cGMP breakdown and amplifying nitric oxide-mediated smooth muscle relaxation—primarily in penile and vascular tissues .
Research Applications & Pharmacology
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Erectile Dysfunction & Andrology Models: Extensively utilized in PDE5-targeting studies focused on sexual function and vascular physiology .
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Cardiovascular & Pulmonary Research: Enables exploration of vasodilatory response and pulmonary hypertension .
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Pharmacokinetics: Oral bioavailability ~15%; protein binding ?95%; liver metabolism via CYP3A4; half-life of 4–5?h .
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Toxicology: Non-carcinogenic up to 100 mg/kg/day in animals; high-dose exposures induced testicular and cardiovascular changes in rodents .
Safety Profile & Handling
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Common Effects: Headache, flushing, nasal congestion, back pain, dizziness.
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Serious Risks: Rare hypotension (especially with nitrates), QT prolongation, priapism .
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Drug Interactions / Contraindications: Avoid co-administration with nitrates, alpha-blockers, or strong CYP3A4 inhibitors in research protocols .
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Handling Instructions: Use PPE, store under recommended conditions, discard expired tablets per lab safety guidelines.
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 18 × 16 × 18 厘米 |
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$2.00
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