Description
Zoledronic acid is a potent bisphosphonate that inhibits osteoclast-mediated bone resorption by targeting farnesyl pyrophosphate synthase. It has been shown to significantly increase bone mineral density in Chinese populations, demonstrating clinical effectiveness equivalent to branded formulations. This research-grade infusion contains 5?mg zoledronic acid in 100?mL of ready-to-use solution, manufactured in sterile conditions.
Packaged in a polypropylene infusion bag, Komigu is manufactured by Sichuan Kelun Pharmaceutical Co., Ltd. and approved for research applications under China’s NMPA licence number H20183157, drug code 86902180002082.
Strictly for laboratory research purposes—not for therapeutic, veterinary, or diagnostic use.
Zoledronic Acid Injection Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Zoledronic Acid Injection (Komigu) |
| Generic Name | Zoledronic Acid |
| CAS Number | 165800?06?6 |
| Molecular Formula | C?H??N?O?P?·H?O |
| Molecular Weight | 290.1?g/mol |
| Dosage Form | Intravenous infusion bag |
| Strength | 5?mg zoledronic acid in 100?mL solution |
| Packaging Unit | Single-use infusion bag |
| Approval Number | H20183157 (China NMPA) |
| Drug Product Code | 86902180002082 |
| Manufacturer | Sichuan Kelun Pharmaceutical Co., Ltd. |
| Intended Use | Laboratory research |
| Storage Conditions | Store at 20–25?°C; stable at controlled room temperature |
Zoledronic Acid Injection Mechanism & Research Applications
Zoledronic acid targets osteoclasts to inhibit bone breakdown by binding to bone mineral surfaces. It has shown effectiveness in increasing bone density and reducing biomarkers of bone resorption in human trials.
Common laboratory research applications include:
Osteoclast activity assays
Bone resorption and mineralization models
In vitro and in vivo bone metabolism studies
Comparative testing against other bisphosphonates
Biomarker analysis for bone turnover (e.g., ?-CTX, P1NP)
Zoledronic Acid Injection Safety & Handling
Use Restriction: For laboratory research only. Not approved for clinical or veterinary use.
Handling: Wear gloves and lab coat; ensure aseptic infusion technique.
Storage: Store sealed at 20–25?°C; protect from freezing and extreme heat.
Disposal: Dispose of unused solution and container per local biosafety protocols.
Core Keywords
Zoledronic acid injection, Komigu zoledronate, 5?mg bisphosphonate infusion, bone resorption research reagent, osteoclast inhibitor injection, laboratory zoledronic acid bag, NMPA H20183157 zoledronic acid, wholesale research bisphosphonate, Sichuan Kelun zoledronic acid
Research Use Disclaimer
This product is for laboratory research use only and not approved for clinical, diagnostic, or veterinary applications. Misuse may present health or regulatory risks. Always adhere to institutional and local biosafety standards.


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