GLP-1/GIP/glucagon combination therapy The Future of Metabolic Treatment (Wholesale Supplier Guide)

GLP-1/GIP/glucagon combination therapy The Future of Metabolic Treatment (Wholesale Supplier Guide)

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GLP-1/GIP/glucagon combination therapy

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描述

Introduction

The GLP-1/GIP/glucagon combination therapy represents a breakthrough in metabolic medicine, offering superior weight loss and glycemic control compared to single-agonist drugs. As a trusted wholesale supplier of peptide therapeutics, we provide high-purity GLP-1, GIP, and glucagon receptor agonists at factory-direct prices for clinics, researchers, and distributors.

This comprehensive guide covers:
Science behind triple-agonist therapy
Key benefits for obesity & diabetes
Wholesale pricing vs. retail costs
How to source premium-quality peptides

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Product Specifications: GLP-1/GIP/Glucagon Combination Peptides

Parameter Details
Active Components Liraglutide (GLP-1), Tirzepatide (GIP/GLP-1), Retatrutide (GLP-1/GIP/Glucagon)
Purity ?98% (HPLC-verified)
Form Lyophilized powder
Solubility Reconstitutes in bacteriostatic water
Storage 2-8°C (lyophilized), -20°C long-term
Shelf Life 24 months
Packaging 2mg, 5mg, 10mg vials (bulk discounts available)

Quality Assurance:

  • Third-party tested for purity, sterility, and endotoxins

  • GMP-certified manufacturing

  • Batch-specific COAs provided


How GLP-1/GIP/Glucagon Combination Therapy Works

1. Triple-Agonist Mechanism

Unlike single-target drugs (e.g., Semaglutide), this approach activates three metabolic pathways:

Receptor Primary Effects
GLP-1 ? Insulin secretion, ? glucagon, slows gastric emptying
GIP Enhances GLP-1 effects, improves fat metabolism
Glucagon Increases energy expenditure via fat oxidation

2. Clinical Advantages Over Single-Agonist Drugs

  • 24%+ body weight loss (vs. 15% with Semaglutide) (Source: NEJM Retatrutide Trial)

  • Faster HbA1c reduction in type 2 diabetes

  • Improved lipid profile (lowers triglycerides, raises HDL

    GLP-1/GIP/Glucagon Combination Therapy – The Future of Metabolic Treatment (Wholesale Supplier Guide)


Key Applications & Benefits

1. Obesity Treatment (Superior to Wegovy®/Mounjaro®)

  • Appetite suppression: Targets brain hunger centers more effectively

  • Metabolic boost: Glucagon increases calorie burning

  • Less muscle loss: Preserves lean mass better than GLP-1 alone

2. Type 2 Diabetes Management

  • Dual glucose control: GLP-1 + GIP synergistically lower blood sugar

  • Cardioprotective effects: Reduces heart disease risk factors

3. Emerging Uses

  • NAFLD/NASH treatment: Reduces liver fat accumulation

  • Neuroprotection: Potential cognitive benefits in Alzheimer’s research


Wholesale Pricing vs. Retail Comparison

Retail Cost (FDA-Approved Brands)

Drug Monthly Price (With Insurance) Cash Price
Wegovy® (GLP-1) $900–$1,300 $1,400+
Mounjaro® (GLP-1/GIP) $1,000–$1,500 $1,600+
Retatrutide* (Future) Estimated $1,200–$1,800 $1,800+

*Not yet FDA-approved (2024 projection)

Wholesale Lyophilized Powder Pricing

Quantity Price per 5mg Vial Savings vs. Retail
1–10 vials $XXX.XX ~60% less
10–50 vials $XXX.XX ~75% less
50+ vials Custom bulk pricing Up to 85% savings

Why Buy Wholesale?

  • Avoid insurance restrictions

  • Ideal for compounding pharmacies

  • Higher profit margins for resellers


How to Use GLP-1/GIP/Glucagon Peptides

Reconstitution Guide

  1. Add 1–2mL bacteriostatic water to lyophilized powder

  2. Gently swirl (don’t shake) until clear

  3. Store reconstituted solution at 2-8°C for ?30 days

Dosing Protocol

  • Weight loss: Start at 0.5mg/week, titrate to 2–5mg/week

  • Diabetes: 0.25mg initial dose, increase to 1–2mg weekly

Always consult a healthcare provider for personalized dosing


Why Source From Us?

Direct GMP-certified factory connection
Batch-specific third-party testing
Bulk discounts (up to 40% off retail)
Discreet global shipping

Limited OfferFree shipping on orders >50 vials

GLP-1/GIP/Glucagon Combination Therapy – The Future of Metabolic Treatment (Wholesale Supplier Guide)

其他信息

重量 2 公斤
尺寸 36 × 60 × 80 厘米

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