Granisetron Hydrochloride Dispersible Tablets Price comparison
$1.00
A 5-HT? receptor antagonist—Granisetron Hydrochloride Dispersible Tablets by Guangxi Mingjian Pharmaceutical Co., Ltd. (Guimingjian). Packaged as 1?mg tablets, 4 tablets per blister × 2 blisters per box. Approved in China (NMPA No. H20020303; product code 86905130000183). Primarily intended for clinical prevention and treatment of nausea/vomiting induced by chemotherapy, radiation, or surgery.
For research use only
描述
Granisetron Hydrochloride Dispersible Tablets Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Granisetron Hydrochloride Dispersible Tablets |
| Formulation | Dispersible film-coated tablet, 1?mg |
| Pack Size | 4 tablets per blister, 2 blisters per box (8 tablets) |
| Approval No. | China NMPA H20020303 |
| Product Code | 86905130000183 |
| Manufacturer | Guangxi Mingjian Pharmaceutical Co., Ltd. |
| Intended Use | Medical/clinical treatment; check local regulations |
Granisetron Hydrochloride Dispersible Tablets Mechanism & Indications
Granisetron is a selective 5?HT? receptor antagonist that blocks serotonin effects on vagal nerve terminals and in the brain’s chemoreceptor trigger zone. It’s indicated for prevention of nausea and vomiting associated with chemotherapy, radiation therapy, and postoperative care webmd.com+7medlineplus.gov+7pdf.hres.ca+7dailymed.nlm.nih.gov.
Granisetron Hydrochloride Dispersible Tablets Pharmacology & Usage
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Dosage: Typically 1?mg orally ~1?hour before chemotherapy or radiation; may repeat dose after 12?hours based on regimen
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Absorption: Oral tablets, dispersible for ease of administration; onset ~30–60?min, half-life ??9?hours
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Metabolism: Primarily via hepatic CYP3A4, excreted in urine (~11% unchanged)
Warnings & Interactions
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Avoid in: Patients with known hypersensitivity to granisetron or excipients.
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QT prolongation: Use caution with drugs affecting cardiac conduction (e.g. SSRIs, antipsychotics, fluconazole)
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Serotonin syndrome: Potential risk when combined with serotonergic agents (e.g., SSRIs, lithium, tramadol) .
Side Effects
From clinical data and pharmacology references:
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Common (?5%): Headache, constipation, diarrhea, fatigue, abdominal discomfort, sleep disturbances
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Serious: Rare QT prolongation, allergic reactions (rash, dyspnea)
Storage & Handling
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Store at 20–25?°C, keep container tightly closed and protected from light
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Dispense in original packaging; each tablet disperses completely in water for ease of ingestion.
References
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MedlinePlus overview on granisetron uses and mechanism
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DailyMed label details: dosage, warnings, pharmacology
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Drugs.com overview: side effects & serotonin warnings
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 18 × 16 × 18 厘米 |
Granisetron Hydrochloride Dispersible Tablets Price comparison 有 1 个评价
A1: One hour before chemotherapy, radiation, or surgery; consult prescribing instructions for potential repeat dosing.
A2: Take as soon as remembered, provided it's within the appropriate timeframe; follow provider guidance.
A3: Pediatric use requires consulting pediatricians. In elderly, dose adjustments generally not needed; monitor for side effects and QT prolongation risk
A4: Yes—there is known hypersensitivity to granisetron or similar medications.
A5: Watch for combinations with QT-prolonging drugs and serotonergics, such as SSRIs, tramadol, or antibiotics like fluconazole
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