Description
Aprepitant Capsules Product Overview
Aprepitant (marketed under Kangrenping) is the world’s first NK1 receptor antagonist antiemetic. Manufactured by Beijing Sihuan Pharmaceutical Co., Ltd., this formulation includes one 125mg capsule and two 80mg capsules per box. Approved by China’s NMPA with drug codes H20243266/H20243265, product code 86900153001025, and barcode 6924330200289. For laboratory research use only—not indicated for clinical or human use. pmc.ncbi.nlm.nih.gov+1viwit.com+1
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Aprepitant Capsules (Kangrenping) |
| Strength | 125mg ×1 & 80mg ×2 capsules per box |
| Formulation | Oral capsule |
| Approval Numbers | H20243266 (125mg), H20243265 (80mg) |
| Product Code | 86900153001025 |
| Barcode | 6924330200289 |
| Manufacturer | Beijing Sihuan Pharmaceutical Co., Ltd. |
| Intended Use | Laboratory research only — Not for human use |
Mechanism of Action
Aprepitant is a neurokinin1 (NK1) receptor antagonist that blocks substance P receptors—key mediators of chemotherapy- and surgery-induced vomiting
Research & Usage Notes
Clinically used to prevent acute and delayed vomiting in CINV and PONV .
Widely studied in pharmacokinetic trials across ethnic groups; safe and well tolerated
The domestic Kangrenping® is China’s 5th approved generic but shows strong market performance (~¥400M/year)
Research Applications
CINV/PONV studies (in vitro PK/PD modeling)
NK?1 receptor binding or antagonist assays
Pharmacokinetic studies & metabolism
CYP3A4 interaction screening
Aprepitant Capsules Handling & Storage
Store at 20–25°C, keep in original packaging
Use standard lab PPE (gloves, mask, etc.)
Avoid ingestion or skin contact


moore –
The effect is good, I will buy from you next month