Description
Regorafenib Tablets Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Regorafenib Tablets |
| Strength | 40mg per tablet |
| Quantity | 28 tablets per bottle |
| Dosage Form | Oral film-coated tablet |
| Approval No. | China NMPA H20243057 |
| Product Code | 86900647000343 |
| Manufacturer | Shanghai Chuannuo Pharmaceutical Co., Ltd. |
| Intended Use | Laboratory research use only—Not for human or veterinary use |
Overview & Mechanism
Regorafenib is a potent multi-kinase inhibitor that targets RTKs critical to tumor growth: VEGFR1/2/3, TIE2, PDGFR, FGFR, KIT, RET, RAF1, BRAF, and CSF1R. It suppresses angiogenesis, proliferation, metastasis, and modulates the tumor immune microenvironment sciencedirect.comoncologynewscentral.com+5stivarga.com+5stivargahcp.com+5de.wikipedia.org+2pmc.ncbi.nlm.nih.gov+2stivargahcp.com+2.
Research & Clinical Background
FDA-approved for metastatic colorectal cancer, GIST, and hepatocellular carcinoma
Shown to extend median overall survival in metastatic colorectal cancer (CORRECT, CONCUR trials) by ~1.4–2.5 months
Demonstrates broad signaling pathway inhibition, including anti-angiogenic and immunomodulatory effects
Research Applications
Ideal for use in:
Angiogenesis and TME modeling
Kinase signaling pathway assays
Drug resistance and combination studies
Metastasis and proliferation models
Pharmacodynamic and bioactivity profiling
Research-Use Disclaimer
This product is provided strictly for laboratory research and development use only.


yaser –
Das Paket ist angekommen, danke