Recombinant Human G?CSF Injection 150??g ×?5 Vials
$1.00
Recombinant human granulocyte colony-stimulating factor (G?CSF, brand: Quansheng®), produced by Shandong Quangang Pharmaceutical Co., Ltd., supports neutrophil recovery in preclinical and post?chemotherapy models. Each 0.6?mL vial contains 150??g of filgrastim-like G?CSF. Initially approved in China on April?16,?2002 (NMPA S20020018; code?86904149000023).
?? For laboratory research use only.?Please consult the staff for other purposes?
描述
Recombinant Human G?CSF Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Recombinant Human G?CSF Injection (Quansheng®) |
| Generic Name | Filgrastim?type recombinant human granulocyte colony-stimulating factor |
| CAS Number | 121181?53?1 |
| Molecular Weight | Approx. 18.8?kDa (non-glycosylated form) |
| Dosage Form | Sterile solution for subcutaneous or intravenous injection |
| Strength | 150??g per 0.6?mL vial |
| Pack Size | 5 vials per box |
| Approval Number | S20020018 (China NMPA) |
| Product Code | 86904149000023 |
| Manufacturer | Shandong Quangang Pharmaceutical Co., Ltd. |
| Storage | Store at 2–8?°C; do not freeze; protect from light |
| Intended Use | Laboratory research use only |
Recombinant Human G?CSF Mechanism of Action
G?CSF binds to the CSF?3 receptor on neutrophil precursors, activating the JAK/STAT and MAPK pathways, which stimulate proliferation, differentiation, maturation, and release of neutrophils from bone marrow.
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Recombinant Human G?CSF Research Applications & Pharmacology
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Chemotherapy-induced neutropenia models: Widely used to study hematologic recovery post-chemotherapy and in stem cell mobilization protocols
en.wikipedia.org -
Stem cell mobilization research: Promotes progenitor cell release for studies in leukapheresis and transplantation
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Pharmacology: Effective doses in beagle dogs at ~20 µg/kg/day; EC50 ~0.05 ng/mL in cell-based bioassays
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Recombinant Human G?CSF Safety Profile & Handling
Preclinical and clinical observations:
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Common effects: Mild bone pain, injection-site redness, occasional fever
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Serious reactions: Splenic enlargement or rupture, rare hypersensitivity
Lab handling tips:
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Store refrigerated and avoid freezing
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Reconstitute under sterile conditions
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Administer SC or IV per model protocol
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Monitor neutrophil counts; biologically active cytokine—use PPE and biological safety procedures
?? Research?Use Disclaimer
This product is intended exclusively for laboratory research purposes. It is not approved for clinical, therapeutic, diagnostic, or veterinary use. Misuse may cause biological risk or compromise experimental data.
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 18 × 16 × 18 厘米 |
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