Description

Product Description

Mannan Peptide Injection is a bioactive laboratory-grade reagent composed of peptide conjugates linked to mannose-rich polysaccharides. Mannan, a component of fungal and yeast cell walls, is recognized by pattern recognition receptors (PRRs) such as mannose-binding lectin and C-type lectin receptors on immune cells. Conjugation with peptides enhances its immunostimulatory properties, making it a valuable tool for investigating host immune responses and antibacterial mechanisms.

This injectable preparation is provided in sterile form for use in cell culture assays, animal models, and preclinical immunology research. It has been extensively used to study:

• Activation of macrophages, dendritic cells, and T lymphocytes;

• Modulation of pro-inflammatory and anti-inflammatory cytokines;

• Enhancement of antigen presentation and adaptive immunity;

• Screening of antimicrobial agents and immunotherapeutics.

Mannan Peptide Injection allows researchers to evaluate bacterial adhesion, immune recognition, and pathogen clearance pathways. Its controlled and standardized composition ensures reproducibility across experiments, reducing variability in immunological outcomes.

The preparation is compatible with multiple experimental approaches, including ELISA, flow cytometry, immunocytochemistry, gene expression profiling, and in vivo animal models. Due to its dual role as a carbohydrate-peptide conjugate, it mimics natural pathogen structures, providing insights into both innate and adaptive immune mechanisms.

Product Specifications

Mechanism of Action

Mannan Peptide Injection functions primarily as an immunomodulatory and antibacterial research agent, acting through the following mechanisms:

1. Innate Immune Activation

Mannan structures are recognized by mannose receptors and C-type lectin receptors on macrophages and dendritic cells, triggering intracellular signaling pathways such as NF-κB. This leads to the secretion of pro-inflammatory cytokines including IL-1β, IL-6, TNF-α, and chemokines that recruit neutrophils and other innate immune cells.

2. Adaptive Immune Modulation

Peptide conjugation enables enhanced antigen presentation via MHC class I and II pathways. Mannan Peptide Injection stimulates T-helper cell polarization, B-cell activation, and antibody production. Researchers can study both humoral and cellular immune responses to antigenic challenges.

3. Antibacterial Mechanisms

Mannan-peptide complexes promote opsonization and phagocytosis of bacteria. They facilitate complement activation and enhance clearance of pathogenic microorganisms in vitro and in vivo. These properties make it suitable for screening antimicrobial agents or vaccine candidates.

4. Cytokine Signaling Regulation

This injection modulates cytokine networks by balancing pro-inflammatory and anti-inflammatory mediators. It can be used to study inflammatory signaling, cytokine storms, and immune tolerance mechanisms in laboratory models.

5. Host-Pathogen Interaction Studies

Mannan Peptide Injection allows detailed investigation of bacterial adhesion, receptor-mediated recognition, and immune evasion strategies. It can be combined with other immunomodulators or antimicrobial compounds to evaluate synergistic or antagonistic effects.

Side Effects

Mannan Peptide Injection is intended strictly for controlled laboratory use. Handling must follow BSL-2 biosafety guidelines. Possible risks include:

• Overactivation of immune cells in vitro or in vivo at high concentrations;

• Cytotoxicity in sensitive cell lines;

• Systemic inflammation in animal models if used improperly.

Proper aseptic techniques, PPE, and biosafety compliance are mandatory. This product is not intended for human or veterinary use.

Keywords

Mannan Peptide Injection, mannoprotein-peptide conjugate, immunomodulatory reagent, antibacterial research, host-pathogen studies, vaccine development, factory biological reagent supplier, high-purity laboratory reagent

Shipping Guarantee

All Mannan Peptide shipments are handled using validated cold-chain logistics to preserve reagent integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We Mannan Peptide ensure product authenticity, verified laboratory-grade purity, and compliance with analytical standards. Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

Payment Support

We Mannan Peptide provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.

Disclaimer

All Mannan Peptide products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.