Vincristine Sulfate 1?mg ×?10 Vials Wholesale price comparison
$2.00
Vincristine Sulfate is a cytotoxic vinca alkaloid used extensively in preclinical oncology research. This lyophilized formulation is indicated for investigational use in tumor biology, particularly leukemia, lymphoma, and neuroblastoma models. Each box contains ten vials, each with 1?mg of Vincristine Sulfate in freeze-dried powder form.
Manufacturer: Shenzhen Wanle Pharmaceutical Co., Ltd.
NMPA Approval Number: H44021772
Product Code: 86900549000014
?? For laboratory research use only.?Please consult the staff for other purposes?
描述
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Vincristine Sulfate for Injection |
| Generic Name | Vincristine Sulfate |
| CAS Number | 2068-78-2 |
| Molecular Formula | C46H56N4O10·H2SO4 |
| Molecular Weight | ~923.04 g/mol |
| Dosage Form | Lyophilized powder for injection |
| Strength | 1?mg per vial |
| Packaging | 1mg × 10 vials per box |
| Indication | Oncology research – leukemias, lymphomas, solid tumors |
| Approval Number | H44021772 (NMPA, China) |
| Product Code | 86900549000014 |
| Manufacturer | Shenzhen Wanle Pharmaceutical Co., Ltd. |
| Storage | 2–8?°C; protect from light |
| Usage | For preclinical laboratory research only |
Mechanism of Action
Vincristine Sulfate inhibits microtubule formation in mitotic spindles by binding to tubulin, causing metaphase arrest and apoptosis in rapidly dividing cells. It is widely used in combination protocols for experimental tumor models.
Research Applications
-
Cancer Research: Acute lymphoblastic leukemia, Hodgkin’s lymphoma, neuroblastoma, and Wilms’ tumor
-
Combination Studies: Used in CHOP, MOPP, or VEC protocols in animal oncology
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Pharmacokinetics: Hepatic metabolism via CYP3A; poor CNS penetration; fecal and renal excretion
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Preclinical Notes: Monitor neurotoxicity and GI tolerance in rodents and canine models
Safety Profile & Handling
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Adverse Effects: Peripheral neuropathy, constipation, leukopenia, hair loss, SIADH
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Fatal Risk: Intrathecal administration is contraindicated—strictly IV use only
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Handling: Use PPE and cytotoxic protocols. Reconstitute with sterile saline. Dispose of as hazardous waste.
?? Research Use Disclaimer
This product is intended solely for scientific research purposes. It is not intended for use in humans or animals as a drug or diagnostic. Misuse may result in harm and is strictly prohibited.
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 18 × 16 × 18 厘米 |
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