Dexmedetomidine Hydrochloride Injection 0.2?mg/2?mL ×?5 Vials (Lyophilized Powder) [For Laboratory Research Use Only]

Dexmedetomidine Hydrochloride Injection 0.2?mg/2?mL ×?5 Vials (Lyophilized Powder) [For Laboratory Research Use Only]

$1.00

Dexmedetomidine hydrochloride is a highly selective ???adrenergic receptor agonist used in preclinical sedation and analgesia research. Each set includes five lyophilized vials of 0.2?mg dexmedetomidine in a 2?mL formulation. Produced by Sinopharm Group Langfang Co., Ltd., approved under NMPA H20203335 (product code: 86902581000113).
?? For laboratory research use only.?Please consult the staff for other purposes?

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描述

Product Specifications

Attribute Details
Product Name Dexmedetomidine Hydrochloride Injection
Generic Name Dexmedetomidine hydrochloride
CAS Number 113775?47?6 ringpu.com+7en.wikipedia.org+7go.drugbank.com+7
Molecular Formula C??H??N?·HCl
Molecular Weight ~236.7?g/mol
Dosage Form Lyophilized powder for injection
Strength 0.2?mg per 2?mL vial
Pack Size 5 vials per box
Approval Number H20203335 (NMPA)
Product Code 86902581000113
Manufacturer Sinopharm Group Langfang Co., Ltd.
Storage Store at 2–8?°C, protect from light
Intended Use Laboratory research only

Mechanism of Action

Dexmedetomidine is a highly selective ???adrenergic agonist (??:?? ?1620:1), producing sedation by decreasing noradrenergic activity in the locus ceruleus and providing analgesia via spinal pathways—without significant respiratory depression.


Research Applications & Pharmacology

  • Sedation & analgesia models: Commonly applied in rodent, canine, and feline models to induce calmness and reduce anxiety or pain pre-procedure .

  • Dosage examples: IM 125–500?µg/m² or IV 375?µg/m² in dogs; IM 40?µg/kg in cats .

  • Pharmacokinetics: High protein binding (~94%), 2–4?hr half-life; hepatic metabolism; excretion via urine.


Safety Profile & Handling

Observed effects:

  • Sedation, mild bradycardia or hypotension, transient respiratory depression in high doses .

  • Avoid mixing with other sedatives to reduce overdose risks.

Handling precautions:

  • Reconstitute per instructions (e.g., to 4?µg/mL for IV infusion) .

  • Use aseptic technique, monitor vitals, and properly dispose of vials as pharmaceutical waste.


?? Research?Use Disclaimer

This product is intended solely for laboratory research. It is not approved for clinical, diagnostic, therapeutic, or veterinary use. Improper usage may compromise subject safety and data validity.

其他信息

重量 1.1 公斤
尺寸 18 × 16 × 18 厘米

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