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Cisatracurium Besilate 10?mg / 5?mL Vial Wholesale price comparison
$23.00
Cisatracurium besilate is an intermediate-acting, non-depolarizing neuromuscular blocking agent used in preclinical research for muscle relaxation, anesthesia modeling, and mechanical ventilation studies. It is one of the 10 stereoisomers of atracurium, offering greater potency and minimal histamine release. Each 5?mL vial contains 10?mg.
?? For laboratory research use only.?Please consult the staff for other purposes?
Description
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Cisatracurium Besilate Injection |
| Generic Name | Cisatracurium Besilate (Nimbex®) |
| CAS Number | 96946?42?8 |
| Molecular Formula | C??H??N?O??S? (besilate salt) |
| Molecular Weight | ~1243.5?g/mol en.wikipedia.org+4accessdata.fda.gov+4en.wikipedia.org+4pdr.net+2en.wikipedia.org+2pfizermedicalinformation.com+2 |
| Dosage Form | Aqueous solution for IV injection |
| Strength | 10?mg per 5?mL vial (2?mg/mL) |
| Pack Size | 1 vial per box |
| Approval Number | H20183042 (China NMPA) |
| Product Code | 86901445002935 |
| Manufacturer | Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
| Barcode | (Not specified) |
| Storage | Refrigerate at 2–8?°C; protect from light |
| Intended Use | Laboratory research only |
Mechanism of Action
Cisatracurium competitively binds to nicotinic cholinergic receptors at the neuromuscular junction, preventing acetylcholine binding and blocking muscle contraction. It is metabolized via Hofmann elimination—organ-independent—making it suitable for varied preclinical models.
Research Applications & Pharmacology
Muscle relaxation models: Suitable for tracheal intubation, ventilation, and anesthesia simulation .
Pharmacokinetics: Onset ~2–4?min; effective duration ~55?min; half-life ~20–30?min; slower onset in geriatrics or renal impairment .
Comparative profile: Less histamine release and hemodynamic impact than atracurium, with faster recovery compared to vecuronium.
Safety Profile & Handling
Adverse events: Minimal histamine-mediated reactions (flushing, hypotension); rare bronchospasm .
Hypersensitivity: Anaphylaxis reported—emergency protocols required .
Lab use guidance: Administer IV with neuromuscular monitoring (e.g., train-of-four), maintain ventilatory support, have resuscitation and reversal agents available .
?? Research?Use Disclaimer
This product is intended exclusively for laboratory research. It is not approved for therapeutic, diagnostic, clinical, or veterinary use. Misuse may pose safety hazards and compromise study validity.
Additional information
| Weight | 1.1 kg |
|---|---|
| Dimensions | 18 × 16 × 18 cm |
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