Description
Ranitidine Hydrochloride Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Ranitidine Hydrochloride Injection (Beite) |
| Synonyms | Ranitidine HCl, Zantac (original brand) |
| CAS Number | 66357-59-3 |
| Molecular Formula | C13H22N4O3S · HCl |
| Molecular Weight | 350.87 g/mol |
| Formulation | Sterile solution for injection |
| Strength | 50 mg/2?mL per ampoule |
| Pack Size | 10 ampoules per box |
| Dosage Form | Injectable solution (Injection) |
| Approval Number | NMPA H32021751 |
| Product Code | 86901708000326 |
| Manufacturer | Chengdu Beite Pharmaceutical Co., Ltd. |
| Storage | Store below 25?°C, protect from light |
| Intended Use | For laboratory research only |
Ranitidine Hydrochloride Mechanism of Action
Ranitidine is a selective histamine H2-receptor antagonist. It inhibits basal and stimulated secretion of gastric acid by blocking H2 receptors on gastric parietal cells, making it suitable for research related to gastric ulcers, acid reflux, and peptic conditions in laboratory models.
Ranitidine Hydrochloride Research Applications & Pharmacology
In vivo gastrointestinal ulcer/acid reflux models
Pharmacodynamic studies of gastric acid suppression
Drug interaction research (e.g., with NSAIDs or antibiotics)
Onset of action: ~1 hour post-injection
Duration: Up to 6–8 hours
Elimination: Primarily renal
Half-life: 2.5–3 hours (species-dependent)
Metabolism: Hepatic and renal excretion
Safety Profile & Handling
Observed effects in preclinical studies:
Hypotension (rare, high doses)
Bradycardia
CNS: dizziness, headache (dose-related)
Hepatic enzyme elevation (in long-term exposure)
Lab Handling Guidelines:
Use appropriate PPE (lab coat, gloves, goggles)
Avoid direct skin/eye contact
Do not inhale vapors or solution
Store away from direct light
Dispose of ampoules per local biohazard protocols
?? Research-Use Disclaimer
This product is intended exclusively for laboratory research purposes. It is not approved for human, clinical, diagnostic, or veterinary use. Any misuse may pose health risks or violate local regulations.


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