描述
Cimetidine Injection Product Specifications
Specification | Description |
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Product Name | Cimetidine Injection (Shanxi Nuocheng) |
Generic Name | Cimetidine |
CAS Number | 51481?61?9 |
Formulation | Lyophilized (freeze-dried) powder for injection |
Strength | 0.2?g cimetidine per 2?mL vial |
Packaging | Box of 2?mL vials |
Approval Number | H20253392 (NMPA, China) |
Product Code | 86905619001090 |
Manufacturer | Shanxi Nuocheng Pharmaceutical Co., Ltd. |
Storage Conditions | Store < 30?°C, dry, protect from light |
Intended Use | For laboratory research only |
Cimetidine Injection Mechanism of Action
Cimetidine is a histamine H? receptor antagonist that selectively inhibits gastric acid secretion by blocking H? receptors on gastric parietal cells, reducing both basal and stimulated release of gastric acid go.drugbank.com+3drugs.com+3scbt.com+3. It competitively binds these receptors to suppress acid production in various gastrointestinal models.
Research Applications & Pharmacology
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Acid suppression model research: GERD, peptic ulcer, Zollinger-Ellison syndrome
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Pharmacodynamic and pharmacokinetic (PD/PK) studies of intravenous dosing
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Drug interaction research due to CYP450 inhibition, especially CYP1A2, CYP2D6, CYP3A4
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Ulcer and reflux modeling in vivo using sterile injection format
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Formulation science using lyophilized process for enhanced stability
Safety Profile & Handling
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Preclinical safety: Generally well-tolerated; acid suppression may alter gastric pH.
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Handling precautions: Use gloves, lab coat, and mask; avoid inhalation and contact with skin/eyes.
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Reconstitution: Add sterile water for injection under aseptic conditions, gently swirl to dissolve.
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Storage: Keep in a cool, dry environment, shielded from light and moisture.
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Disposal: Dispose according to hazardous or biohazard-lab waste protocols.
Core Keywords
Cimetidine injection, H? receptor antagonist, lyophilized powder injection, gastric acid research, laboratory cimetidine, CAS 51481-61-9, wholesale cimetidine, Shanxi Nuocheng cimetidine
Research-Use Disclaimer
This product is intended exclusively for laboratory research. It is not approved or suitable for clinical, therapeutic, diagnostic, or veterinary use. Improper handling or unauthorized application may pose serious health risks. Please abide by institutional safety guidelines.
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