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Roxatidine Acetate Hydrochloride 75?mg Freeze?Dried Powder ×10 Vials (WeiDing / Shuanghe)
$3.00
Roxatidine Acetate Hydrochloride Injection (WeiDing/Shuanghe) is a sterile lyophilized powder, 75?mg per vial, 10 vials per box. Manufactured by Shuanghe Pharmaceutical (Hainan) Co., Ltd., approved under NMPA H20244064. A potent and specific H? receptor antagonist used for experimental gastrointestinal acid suppression, allergy/inflammation, mast-cell signaling and NF-?B pathway research.?? Strictly for laboratory research use only. ?Please consult staff for other specifications and uses?
Description
Roxatidine Acetate Hydrochloride Product Specifications
| Specification | Description |
|---|---|
| Product Name | Roxatidine Acetate Hydrochloride Injection (WeiDing / Shuanghe) |
| Generic Name | Roxatidine Acetate HCl |
| CAS Number | 93793?83?0 |
| Molecular Formula | C??H??N?O? · HCl |
| Molecular Weight | 384.90?g/mol |
| Formulation | Freeze?dried powder for injection |
| Strength | 75?mg per vial |
| Pack Size | 10 vials per box |
| Approval Number | H20244064 (NMPA, China) |
| Product Code | 86905843001705 |
| Manufacturer | Shuanghe Pharmaceutical (Hainan) Co., Ltd. |
| Barcode | Contact online pharmacist to submit |
| Storage Conditions | Store below 30?°C, dry, light?protected |
| Intended Use | For laboratory research only |
Roxatidine Acetate Hydrochloride Mechanism of Action
Roxatidine is a specific and competitive histamine H?-receptor antagonist, inhibiting gastric acid secretion and ulcer formation. It’s also noted to suppress inflammatory signaling such as NF-?B and p38 MAPK in mast-cell-mediated allergy models
Research Applications & Pharmacology
Gastrointestinal acid suppression: Effective in duodenal and gastric ulcer models, comparable to ranitidine jstage.jst.go.jp+3pubmed.ncbi.nlm.nih.gov+3pubmed.ncbi.nlm.nih.gov+3.
Allergy & inflammation: Demonstrates reduction of mast cell cytokines and NF-?B/p38 MAPK signaling in allergic models .
Mast-cell studies: Blocks histamine release and inflammatory mediator production in vitro and in vivo.
Signal pathway research: Excellent tool to study H? receptor pathways and downstream effects in pharmacological experiments.
Roxatidine Acetate Hydrochloride Safety Profile & Handling
Preclinical safety: Generally well tolerated; mild GI or headache signs noted in humans.
Handling: Use PPE (gloves, lab coat, eye protection); reconstitute under aseptic conditions.
Storage: Store sealed, protect from light and moisture, maintain <?30?°C.
Disposal: Dispose of vials per chemical and biohazard waste regulations.
Core Keywords
roxatidine injection, H? receptor antagonist, roxatidine acetate HCl, CAS 93793-83-0, gastric ulcer research, allergy inflammation model, mast cell signaling, wholesale roxatidine
Research?Use Disclaimer
This product is intended exclusively for laboratory research. It is not approved for clinical, therapeutic, diagnostic, or veterinary use. Improper handling may pose health risks. Follow institutional and chemical safety protocols.
Additional information
| Weight | 1 kg |
|---|---|
| Dimensions | 28 × 26 × 28 cm |
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