Description
Lemborexant Tablets (brand name: Dayvigo ) contain 10?mg per tablet, with 28 tablets per box. Manufactured by Eisai Manufacturing Ltd. (UK), and approved in China under NMPA HJ20250057. This compound is an orexin receptor antagonist used in sleep, CNS, and circadian rhythm disorder research models.
?? For research use only. Not for human or veterinary consumption.
Lemborexant (Dayvigo) is a dual orexin receptor antagonist (DORA) that selectively binds to OX1R and OX2R receptors, blocking wake-promoting neuropeptides. This action helps induce sleep and maintain sleep duration. In research, it is used to investigate:
Insomnia mechanisms
Circadian rhythm dysregulation
Neurotransmitter signaling in sleep-wake cycles
Hypothalamic neural circuitry
Lemborexant Tablets Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Lemborexant Tablets (Dayvigo / ???) |
| Generic Name | Lemborexant |
| CAS Number | 1369764-02-2 |
| Molecular Formula | C22H20F1N5O2 |
| Molecular Weight | 405.43?g/mol |
| Formulation | Oral tablet |
| Strength | 10?mg per tablet |
| Pack Size | 28 tablets (2 blisters × 14 tablets) |
| Dosage Form | Tablet |
| Approval Number | HJ20250057 (China NMPA) |
| Pharmaceutical Code | 86979086000771 |
| Manufacturer | Eisai Manufacturing Ltd., UK |
| Storage | Store in a cool, dry place (15–25?°C), avoid light and heat |
| Intended Use | Laboratory research only |
Lemborexant Tablets Mechanism of Action
Lemborexant is a dual orexin receptor antagonist (DORA), inhibiting both OX1R and OX2R receptors. These receptors regulate wakefulness, and their inhibition decreases neuronal activity in the arousal centers of the brain, enabling sleep induction and maintenance.
Its selective, non-sedative profile makes it ideal for sleep architecture studies, REM/non-REM analysis, and drug interaction models.
Research Applications
Sleep-onset and sleep-maintenance insomnia
Orexin pathway studies
Circadian rhythm dysfunction
Jet lag and shift work disorder
Comparative hypnotic pharmacology
Neuropsychiatric disorder research (depression, anxiety)
Safety & Handling
Lab use only; not for ingestion
Use personal protective equipment (PPE)
Avoid exposure to eyes, skin, or mucosa
COA and SDS available on request
Research Use Disclaimer
This product is intended exclusively for research use. It is not approved for clinical, therapeutic, or veterinary use. Misuse may lead to health risks. Follow all safety guidelines and local regulations.


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