Description
Zolmitriptan is commonly used as a reference compound in preclinical research targeting migraines and vascular regulation in the brain. It offers strong selectivity toward 5-HT?B/?D receptors, helping model and investigate neurovascular inflammation and trigeminal activation.
Zolmitriptan Tablets Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Zolmitriptan Tablets |
| Generic Name | Zolmitriptan |
| CAS Number | 139264?17?8 |
| Molecular Formula | C16H21N3O2 |
| Molecular Weight | 287.36?g/mol |
| Strength | 2.5?mg per tablet |
| Formulation | Oral tablet |
| Pack Size | 1 blister × 10 tablets per box |
| Approval Number | H20051234 (NMPA, China) |
| Drug Code | 86905836000173 |
| Manufacturer | Hainan Haishen Tongzhou Pharmaceutical Co., Ltd. |
| Storage Conditions | Store in a dry place below 25?°C |
| Intended Use | For laboratory research only |
Zolmitriptan Tablets Mechanism of Action
Zolmitriptan is a selective serotonin receptor agonist targeting 5?HT?B and 5?HT?D subtypes. It constricts cranial blood vessels, inhibits pro-inflammatory neuropeptide release, and reduces trigeminal nerve activation. These actions make it a key molecule in migraine and headache-related pharmacological research.
Zolmitriptan Tablets Research Applications
Migraine Pathophysiology Studies
Used to simulate vasoconstriction and trigeminal nerve pathway mechanisms in animal or ex vivo models.Serotonergic Receptor Research
Helps analyze 5?HT receptor subtype selectivity and downstream effects in CNS signaling.Neurovascular Imaging
Applied in neuroimaging trials to study blood–brain barrier permeability and neuroinflammation.Analgesic and Anti-inflammatory Models
Relevant in preclinical evaluation of anti-headache, anti-nociceptive effects.
Safety Profile & Handling
Lab Observations: Possible behavioral changes such as reduced locomotion or sedation in animal studies.
Handling Instructions: Use nitrile gloves, protective eyewear, and dust-proof equipment during handling.
Shelf Life: 36 months from production when stored in sealed packaging under recommended conditions.
Core Keywords
Zolmitriptan, Zolmitriptan Tablets 2.5mg, CAS 139264-17-8, 5HT1B agonist, 5HT1D agonist, migraine research compound, triptan analogue, CNS pharmacology, lab-use zolmitriptan, wholesale research chemicals
Research-Use Disclaimer
This product is intended strictly for laboratory research use only. It is not approved for use in humans or animals. Misuse may pose health hazards. Ensure compliance with institutional safety protocols and handling regulations.


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