Description
Quetiapine Fumarate Tablets Product Specifications
| Parameter | Description |
|---|---|
| Product Name | Quetiapine Fumarate Tablets |
| Active Ingredient | Quetiapine Fumarate |
| Strength | 200mg (0.2g) per tablet |
| Form | Oral Tablets |
| Pack Size | 20 tablets per box |
| CAS Number | 111974-72-2 |
| Molecular Formula | C??H??N?O?S·C?H?O? |
| Molecular Weight | ~883.1 g/mol (as fumarate salt) |
| Dosage Form | Solid (film-coated tablet) |
| Approval Number | NMPA H20233800 |
| Pharmaceutical Code | 86904561001264 |
| Manufacturer | Ningbo Tianheng Pharmaceutical Co., Ltd. |
| Storage Conditions | Store in a cool, dry place; avoid direct sunlight |
| Intended Use | Laboratory research use only |
Quetiapine Fumarate Tablets Mechanism of Action
Quetiapine is a second-generation (atypical) antipsychotic that antagonizes multiple neurotransmitter receptors, including serotonin 5-HT2A, dopamine D2, histamine H1, and adrenergic receptors. Its action on the dopaminergic and serotonergic systems makes it suitable for use in schizophrenia and mood disorder models.
Research Applications
Schizophrenia Research: Used in behavioral and neurochemical animal models to study positive and negative symptoms.
Bipolar Disorder Studies: Explored in models simulating manic and depressive phases.
Sleep and Mood Regulation: Quetiapine is studied for its sedative effects via H1 and 5-HT2A blockade.
Pharmacokinetics Studies: Assessed for its metabolic profile, bioavailability, and receptor binding in vivo.
Neuroprotection Models: Investigated for oxidative stress modulation and neuronal apoptosis reduction.
Safety & Handling
Handling Instructions: Use gloves and appropriate lab PPE. Avoid inhalation or contact with skin.
Storage: Keep sealed at room temperature in a low-humidity environment.
Stability: Stable under recommended storage conditions for 24 months from manufacturing date.
Hazard Warnings: Research-use only. Avoid improper disposal or unauthorized handling.
Research-Use Disclaimer
This product is intended exclusively for scientific laboratory research. It is not certified for human use, animal use, or therapeutic applications. Misuse may lead to legal or health consequences. Always comply with institutional safety protocols and regional regulations.


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