No products in the cart.
Agomelatine Tablets 25?mg (Pusike ) Low price wholesale
$2.00
Agomelatine (brand name: Pusike ) is a melatonergic antidepressant agent presented as 25?mg oral tablets. Manufactured by Shandong Jingwei Pharmaceutical Co., Ltd., this compound is used for laboratory research into circadian rhythm, depression, and melatonin receptor studies. Each box contains 14 tablets.?? Strictly intended for scientific research use only.?Please consult staff for other specifications and uses?
Description
Agomelatine is a novel antidepressant with a dual mechanism of action as a melatonin receptor agonist (MT?/MT?) and serotonin 5-HT?C receptor antagonist. It is widely studied in research involving mood regulation, neurogenesis, sleep-wake cycles, and chronobiology.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Agomelatine Tablets |
| Brand Name | Pusike |
| Active Ingredient | Agomelatine |
| CAS Number | 138112-76-2 |
| Molecular Formula | C15H17NO2 |
| Molecular Weight | 243.3 g/mol |
| Strength | 25?mg per tablet |
| Formulation | Oral tablets |
| Pack Size | 14 tablets per box |
| Approval Number | H20249128 (NMPA, China) |
| Drug Code | 86904111000617 |
| Manufacturer | Shandong Jingwei Pharmaceutical Co., Ltd. |
| Storage Conditions | Store in a cool, dry place (15–25°C); protect from light |
| Research Use | Laboratory research only |
Mechanism of Action
Agomelatine exhibits a dual mechanism:
Agonist at MT? and MT? receptors, promoting circadian rhythm normalization.
Antagonist at 5-HT?C receptors, resulting in increased dopamine and norepinephrine release in the frontal cortex.
This unique action is useful in research models of depression, sleep disturbance, and neurochemical imbalance.
Research Applications
Depression & Mood Disorders
Used in preclinical models simulating major depressive disorder (MDD) and seasonal affective disorder (SAD).Sleep-Wake Cycle Studies
Improves sleep onset and continuity in animal circadian disruption models.Neuroplasticity & BDNF
Shown to upregulate BDNF expression, supporting studies on neuroregeneration.Non-serotonergic Antidepressant Research
Useful for investigating alternative antidepressant pathways without SSRI-like adverse effects.
Safety & Handling
Handling: Use gloves and protective equipment. Avoid direct contact with tablet powder.
Storage: Keep sealed at room temperature. Protect from humidity.
Stability: Shelf-stable for up to 36 months under recommended conditions.
Toxicology: At high doses in lab settings, may cause hepatotoxic effects—handle with caution in long-term studies.
Research Use Disclaimer
This product is intended exclusively for laboratory research purposes. It is not approved for human, clinical, or veterinary application. Users must follow institutional guidelines and local laws. Improper use may result in serious health risks.
Additional information
| Weight | 1.2 kg |
|---|---|
| Dimensions | 42 × 36 × 42 cm |
Q1: What is the CAS number of Agomelatine?
A1: The CAS number is 138112-76-2, used for accurate compound tracking and database referencing.
Q2: Is this product for clinical treatment?
A2: No. This version is strictly for laboratory and experimental use, not for human administration.
Q3: How does Agomelatine differ from SSRIs?
A3: Unlike SSRIs, Agomelatine does not inhibit serotonin reuptake but modulates circadian rhythm and enhances dopamine/noradrenaline indirectly.
Q4: Can I purchase this in bulk for institutional research?
A4: Yes. We offer bulk and OEM supply options. Contact us directly for volume pricing and logistics.
Q5: Do you offer COA and SDS documents?
A5: Yes, Certificates of Analysis and Safety Data Sheets are available upon request.
Related products
Zolmitriptan Tablets 2.5?mg × 10 Tablets Factory low price wholesale
Zolmitriptan is a serotonin (5?HT?B/?D) receptor agonist widely used in laboratory research on migraine pathophysiology and central nervous system (CNS) vasoregulation. Manufactured by Hainan Haishen Tongzhou Pharmaceutical Co., Ltd., each tablet contains 2.5?mg of active ingredient. This product is provided in a 10-tablet box, approved under NMPA H20051234.?? Strictly for laboratory research use only.?Please consult staff for other specifications and uses?
$1.00Aripiprazole for Injection Lyophilized powder 0.3g Low price wholesale
Aripiprazole for Injection is a freeze-dried powder formulation containing 0.3g of Aripiprazole per vial. Manufactured by Otsuka Pharmaceutical Co., Ltd. (Tokushima Wajiki Factory), Japan. Approved under HJ20230054 in China. This dopamine D2 receptor partial agonist is commonly studied in psychopharmacology and neurochemical behavior research.?? For laboratory research use only.?Please consult staff for other specifications and uses?
$2.00Trazodone Hydrochloride Tablets 25?mg Low price wholesale
Trazodone Hydrochloride Tablets (Anshi ) contain 25?mg of trazodone HCl each, totaling 100 tablets per box (20?×?5 blisters). Manufactured by Shenyang Funing Pharmaceutical Co., Ltd. under NMPA H20060037, these tablets are ideal for preclinical research on mood disorders, SSRIs, and serotonin-related mechanisms.?? For laboratory research use only.?Please consult staff for other specifications and uses?
$16.00Pregabalin Capsules SCPC 75?mg Wholesale Price Comparison
Pregabalin Capsules 75?mg ×?8 are used in laboratory research related to neuropathic pain, epilepsy, and anxiety disorders. This CNS-active molecule is a GABA analogue with selective activity at voltage-gated calcium channels. Manufactured by Sichuan Pharmaceutical Formulation Co., Ltd., and approved under NMPA registration H20233922.?? Strictly for laboratory research use only.?Please consult staff for other specifications and uses?
$2.00
Reviews
There are no reviews yet.