Description

Tiopronin (N?(2?mercaptopropionyl)glycine) is a thiol?containing amino acid derivative known for its antioxidant, detoxifying, and metal?chelating effects. Sulpronin Injection is used in laboratory models of liver protection, toxin clearance (e.g., heavy metals), and mitigation of chemotherapy/radiotherapy side effects. It contributes to glutathione replenishment, reduces oxidative stress, and improves hepatic enzyme markers.

Tiopronin Sodium Specifications

Tiopronin Sodium Mechanism of Action

Tiopronin’s free thiol group enables it to act as an antioxidant by scavenging reactive oxygen species and supporting glutathione regeneration. It chelates heavy metals and binds reactive metabolites, promoting liver protection and detoxification.

Tiopronin Sodium Research Applications

• Acute and chronic hepatitis models

• Fatty liver and alcohol-induced injury research

• Drug-induced and heavy metal-induced hepatotoxicity studies

• Radiotherapy/chemotherapy toxicity mitigation

• Biomarker research (ALT/AST reduction)

Safety & Handling

• Experimental Dose: Fast IV infusion at 0.1–0.2?g once daily for 4 weeks in rodent studies

• Side Effects: Generally mild; nausea/headache are rare

• Contraindications: Known hypersensitivity to thiol compounds

• Storage: Store at 2–8?°C, avoid freezing and light exposure

• Handling: Use sterile technique and standard lab PPE

Core Keywords

tiopronin injection, sulpronin sodium, CAS 1953-02-2, hepatoprotective thiol injection, detox antioxidant injection, H20067498, lab-grade tiopronin, wholesale sulpronin

Research Use Disclaimer

This product is intended solely for laboratory and preclinical research. It is not approved for clinical, therapeutic, diagnostic, or veterinary use. Misuse may have legal or health consequences. Use under appropriate institutional protocols.