Description

Calcitriol (1,25-dihydroxyvitamin D?) is the biologically active form of vitamin D. It plays a critical role in regulating calcium and phosphate metabolism by increasing intestinal calcium absorption, reducing calcium excretion, and promoting bone mineralization.

The GanTong formulation offers a consistent 0.25??g per capsule in softgel form, enabling precise administration for preclinical and pharmacological studies. This product is manufactured under NMPA approval by Sichuan Guowei Pharmaceutical Co., Ltd. and is suitable for a wide range of CNS, renal, and bone metabolism research.

?? Strictly for laboratory research only. Not for therapeutic, diagnostic, or human use.

Calcitriol Soft Product Specifications

Calcitriol Soft Mechanism of Action

Calcitriol activates the vitamin D receptor (VDR), which regulates transcription of genes involved in calcium absorption and bone remodeling. It is commonly used in laboratory settings to:

• Enhance calcium and phosphate uptake

• Promote bone cell differentiation

• Study renal osteodystrophy and osteoporosis models

• Investigate immune and endocrine regulation

Calcitriol Soft Research Applications

• Bone metabolism and calcium regulation

• Chronic kidney disease–mineral bone disorder (CKD-MBD) studies

• Osteoporosis and vitamin D metabolism models

• Hormone receptor signaling and VDR pathway analysis

• In vitro and animal model endocrinology studies

Side Effects (Observed in Research Contexts)

• Hypercalcemia

• Nausea, fatigue, or muscle weakness in high concentrations

• Renal load or calcification with excessive accumulation

• Dermal irritation on direct contact

Handle with care using PPE in all laboratory settings.

Safety & Handling

• Use: Laboratory research only

• Protective Measures: Gloves, lab coat, fume hood where appropriate

• Storage: Refrigerate at 2–8?°C

• Shelf Life: Use before expiry date as printed on the package

• Disposal: Follow institutional chemical waste protocols

Core Keywords

Calcitriol soft capsules, GanTong vitamin D3, 0.25??g calcitriol, calcitriol for lab use, research-grade vitamin D, CAS 32222-06-3, Sichuan Guowei calcitriol, wholesale calcitriol capsules, bone metabolism research, VDR pathway studies

Research Use Disclaimer

This product is intended for research use only. It is not approved for therapeutic, diagnostic, clinical, or veterinary use. Misuse may pose health or legal risks. Please follow local laws and laboratory safety protocols.