Description
Leflunomide is a pyrimidine synthesis inhibitor widely studied in autoimmune and inflammatory disease research. It acts primarily by suppressing dihydroorotate dehydrogenase (DHODH), leading to reduced T-cell proliferation and cytokine activity.
The Hepai formulation delivers precise 10mg doses per tablet, packaged in a 12-tablet box. Manufactured by Meheco Moroy Pharmaceutical Co., Ltd., approved by China’s NMPA under drug license H20223506 and base code 86901122000988. Barcode: 6927374200017.
?? This product is for laboratory research only. Not intended for human or veterinary use.
Leflunomide Tablets Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Leflunomide Tablets (Hepai) |
| Generic Name | Leflunomide |
| CAS Number | 75706-12-6 |
| Molecular Formula | C??H?F?N?O? |
| Molecular Weight | 270.21?g/mol |
| Dosage Form | Tablet |
| Strength | 10mg per tablet |
| Quantity | 12 tablets per box |
| Approval Number | H20223506 (China NMPA) |
| Product Code | 86901122000988 |
| Manufacturer | Meheco Moroy Pharmaceutical Co., Ltd. |
| Barcode | 6927374200017 |
| Intended Use | Laboratory research only |
| Storage Conditions | Store below 25°C in a dry, sealed environment |
Leflunomide Tablets Mechanism & Research Applications
Leflunomide selectively inhibits DHODH, an essential enzyme for de novo pyrimidine biosynthesis in lymphocytes. By limiting DNA/RNA precursor availability, it dampens immune cell proliferation and inflammatory signaling.
Applications include:
Rheumatoid arthritis (RA) modeling
Autoimmune disorder studies
Inflammation and cytokine pathway inhibition
T-cell and macrophage suppression
Signal transduction and immunosuppressive compound screening
Leflunomide Tablets Side Effects (Observed in Research Models)
Elevated liver enzyme markers with prolonged use
Gastrointestinal disturbances: diarrhea, abdominal discomfort
Teratogenicity in animal reproduction studies
Hematologic changes under chronic exposure
Transient fatigue or weight fluctuation in high-dose groups
All experimental use should comply with local animal care and lab safety protocols.
Safety & Handling
Use Restriction: Laboratory research only
Personal Protection: Gloves, goggles, lab coat required
Storage: Keep sealed and dry, under 25°C
Disposal: Dispose in accordance with chemical waste regulations
Core Keywords
Leflunomide tablets, Hepai leflunomide, 10mg autoimmune research compound, DHODH inhibitor for lab use, inflammation inhibitor tablets, NMPA H20223506 Leflunomide, Meheco Moroy pharmaceutical tablets, research-grade immunosuppressive agent
Research Use Disclaimer
This product is not approved for clinical, diagnostic, or therapeutic use in humans or animals. For laboratory research only. Handle with proper safety equipment and follow institutional biosafety protocols.


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