描述
Junmaikang® is a biosimilar of adalimumab, a fully human monoclonal antibody targeting TNF??, approved by China’s NMPA (approval number S20220008) . Manufactured by Suzhou Zhonghe Biomed Tech Co., Ltd., it mirrors the therapeutic action of Humira®, and is widely used in research exploring autoimmune pathways, inflammation, and immune modulation.
Available as a single-use 0.8?mL prefilled syringe containing 40?mg adalimumab, it supports in vitro and in vivo laboratory research—such as cytokine inhibition assays, arthritis models, immune cell signaling pathways, and TNF?? neutralization studies.
Adalimumab Injection Product Specifications
Parameter | Details |
---|---|
Product Name | Adalimumab Injection (Junmaikang) |
Generic Name | Adalimumab (TNF?? Monoclonal Antibody Biosimilar) |
CAS Number | 331731?18?1 |
Molecular Formula | Protein (monoclonal antibody ~148?kDa) |
Dosage Form | Prefilled syringe |
Strength | 40?mg in 0.8?mL |
Packaging | 1 syringe per box |
Approval Number | S20220008 (China NMPA) |
Product Code | 86981823000043 |
Manufacturer | Suzhou Zhonghe Biomed Tech Co., Ltd. |
Intended Use | Laboratory research only |
Storage Conditions | Refrigerate at 2–8?°C; protect from light |
Barcode | (Not specified) |
Adalimumab Injection Mechanism & Research Applications
Adalimumab (Junmaikang) functions by binding to TNF??, blocking its interaction with cell receptors, thereby inhibiting inflammatory signaling cascades. As an NMPA-approved biosimilar, it’s suitable for:
-
TNF?? neutralization assays
-
Autoimmune disease models (arthritis, colitis)
-
Inflammatory cytokine modulation studies
-
Immunology and cell signaling research
-
Comparative analysis with reference adalimumab
Adalimumab Injection Observed Effects & Preclinical Notes
While primarily a research agent, adalimumab has shown:
-
In vivo reduction of TNF?? levels and inflammatory markers
-
Modulation of immune cell function
-
Minimal immunogenic responses in validated animal models
Researchers should monitor dose responses and manage biosafety per institutional guidelines.
Safety & Handling Guidelines
-
Use Restriction: Laboratory research only — not for human or veterinary use
-
PPE Required: Gloves, lab coat, safety goggles
-
Storage: Keep refrigerated at 2–8?°C; avoid freezing and light exposure
-
Disposal: Dispose as biohazardous material per institutional protocols
Research Use Disclaimer
This product is strictly for laboratory research use only. It is not intended for human or veterinary treatment, clinical diagnosis, or use. Misuse may result in serious legal and health consequences. Handle according to biosafety and institutional regulations.
评价
目前还没有评价