Description
Product Description
Icotrokinra is a synthetic peptide-based compound developed for advanced pharmaceutical and immunological research. As a novel molecular entity, has attracted increasing attention in inflammatory pathway modulation, immune response regulation, and peptide drug discovery studies.
From a structural perspective, Icotrokinra is designed to exhibit high receptor selectivity and optimized biological stability. Its peptide backbone enables predictable conformational behavior, which supports consistent receptor interaction and signaling pathway modulation in experimental models. This stability also makes suitable for formulation and delivery system research.
In immunology and inflammation-related studies, Icotrokinra is commonly applied to investigate cytokine signaling regulation, immune cell activation pathways, and inflammatory mediator balance. These studies contribute to a deeper understanding of immune response mechanisms and peptide-based therapeutic strategies.
In pharmaceutical research, Icotrokinra serves as a reference compound for peptide optimization, structure–activity relationship analysis, and delivery technology development. Its compatibility with lyophilization and injectable formulation systems allows researchers to evaluate excipient interactions, stability profiles, and sustained-release strategies.
Icotrokinra is also valuable in preclinical assay development, including receptor binding studies, cell-based functional assays, and pathway screening models. Its reproducible chemical properties support experimental consistency across different research batches.
To ensure reliable research outcomes, Icotrokinra raw material is produced with strict quality management, comprehensive analytical validation, and batch-level documentation. This allows researchers and formulation scientists to conduct studies with confidence in material consistency and traceability.

Product Specifications
| Item | Description |
|---|---|
| Product Name | Icotrokinra |
| Synonyms | JNJ-77242113; JNJ-2113; PN-235 |
| CAS Number | 2763602-16-8 |
| Molecular Formula | C90H120N20O22S2 |
| Molecular Weight | 1898.17 g/mol |
| Amino Acid Sequence | Proprietary cyclic peptide sequence (IL-23R antagonist) |
| Peptide Type | Synthetic macrocyclic peptide |
| Form | Lyophilized powder |
| Purity | ≥99% (HPLC) |
| Strength Options | Customized upon request |
| Appearance | White to off-white solid |
| Identity Verification | HPLC, MS |
| Solubility | Soluble in water / DMSO |
| Packaging | Sterile glass vial |
| Storage Condition | −20 °C, protected from light |
| Intended Use | Research use only |
Applications
Icotrokinra is mainly applied in the following research fields:
Inflammatory signaling pathway research
Cytokine modulation studies
Immune cell activation and regulation models
Peptide drug discovery and screening
Structure–activity relationship analysis
Peptide formulation and stability research
Sustained-release delivery system evaluation
Preclinical pharmacological modeling
Its well-defined peptide structure and high purity make Icotrokinra suitable as a reference compound in advanced immunological and pharmaceutical research.

Packaging
Supplied in sterile, sealed glass vials with complete batch labeling. Customized vial size, labeling, and secondary packaging are available for bulk research supply.

Storage & Transportation
Store at -20°C in a dry, light-protected environment. Cold-chain transportation is recommended to maintain peptide integrity during shipment.
Inquiry & Technical Consultation
For COA, MS spectra, HPLC chromatograms, stability data, or batch-specific technical documentation of Icotrokinra, please submit your inquiry through the contact form. Our technical team will provide professional support for your research projects.
Disclaimer
This product is intended for research use only. It is not approved for human or veterinary use. All experimental applications must comply with applicable regulatory and institutional requirements.







daltonbaillie –
The product arrived well packaged and in perfect condition. Delivery was faster than expected, and the overall quality meets our expectations. Would consider ordering again.