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Trofinetide Peptide – Purity 99.90% | GMP Factory Wholesale Supply
$2.00
Trofinetide (NNZ-2566) is a synthetic analog of the neuropeptide GPE, demonstrating potent anti-inflammatory and neuroprotective properties. Manufactured under GMP with 99.90% purity—ideal for neuroscience, neurodevelopmental, and Rett syndrome research. Laboratory use only.
Description
Product Description
Trofinetide is a synthetic analog of the N-terminal tripeptide of insulin-like growth factor 1 (IGF-1), developed for scientific research related to neurotrophic signaling and neuronal function. Due to its defined molecular structure and stability, it is widely used in laboratory settings to explore mechanisms associated with neuronal development, synaptic regulation, and neuroprotective pathways.
In research environments, Trofinetide is frequently employed to study IGF-1–related signaling cascades without activating full mitogenic effects. This characteristic allows researchers to isolate specific neurotrophic responses while minimizing confounding cellular proliferation signals. As a result, the peptide is valuable in mechanistic studies of neuronal connectivity, synaptic plasticity, and intracellular signaling modulation.
Trofinetide is also utilized in experimental models examining neurodevelopmental processes and central nervous system regulation. Its reproducible biochemical behavior supports controlled experimentation across in vitro neuronal cultures and in vivo research models designed to investigate neurological function.
Supplied as a high-purity raw material, Trofinetide enables flexible experimental design, including dose–response evaluations, pathway-specific analysis, and comparative studies with related neurotrophic peptides. Each production batch undergoes comprehensive analytical testing to ensure identity, purity, and batch-to-batch consistency suitable for advanced research use.
Product Specifications
| Item | Description |
|---|---|
| Product Name | Trofinetide |
| Synonyms | NNZ-2566 |
| CAS Number | 853400-76-7 |
| Molecular Formula | C14H24N6O4 |
| Molecular Weight | ~340.4 g/mol |
| Amino Acid Sequence | Gly-Pro-Glu |
| Peptide Type | Synthetic peptide |
| Form | Lyophilized powder |
| Purity | ≥99% (HPLC) |
| Strength Options | Customizable (mg scale) |
| Appearance | White to off-white powder |
| Identity Verification | HPLC, MS |
| Solubility | Soluble in water or suitable buffers |
| Packaging | Sterile glass vial |
| Storage Condition | −20 °C, protected from light |
| Intended Use | Research use only |
Applications
Trofinetide is primarily applied in experimental research related to neurotrophic and neurological signaling.
Common research applications include:
Neurotrophic signaling pathway studies
Neuronal development and differentiation research
Synaptic plasticity investigations
IGF-1–related signaling modulation studies
Neuroprotection mechanism research
Central nervous system research models
In vitro neuronal culture experiments
In vivo neurological research models
These applications support its role as a reference peptide in neuroscience-focused research programs.
Packaging
The product is supplied in sterile, sealed glass vials containing lyophilized peptide material. Bulk quantities and customized packaging options are available to support institutional and laboratory research needs.
Storage & Transportation
Store at −20 °C in a dry, light-protected environment. Avoid repeated freeze–thaw cycles. Cold-chain transportation is recommended to preserve peptide stability.
Inquiry & Technical Consultation
For Certificates of Analysis, batch documentation, or technical consultation related to Trofinetide, please submit an inquiry through the contact form. Technical support is available for qualified research users.
Disclaimer
This product is intended for research use only.
Not for human or veterinary use.
All experimental handling must comply with applicable laboratory and regulatory requirements.
Additional information
| Weight | 0.8 kg |
|---|---|
| Dimensions | 29 × 22 × 29 cm |
What is Trofinetide?
Trofinetide is a synthetic analog of the GPE neuropeptide with neuroprotective and anti-inflammatory actions.
What is the CAS number of Trofinetide?
The CAS number is 853400-76-7.
How does Trofinetide work in neuroscience research?
It suppresses key inflammatory cytokines and supports synaptic health and function in disease models.
What are its primary research applications?
Used in Rett syndrome modeling, neuroinflammation, and brain injury studies.
Is this product made to GMP standards?
Yes—it is manufactured under GMP conditions.
What purity does this product offer?
This batch has a high purity of 99.90%.
What side effects have been observed?
Diarrhea and vomiting are most common; slow titration improves tolerability in clinical settings.
Can Trofinetide be used clinically?
No—it is labeled for research use only.
How should it be stored?
Store at –20 °C, protected from light and moisture.
Why is Trofinetide relevant in Rett syndrome research?
It is FDA-approved for RTT, demonstrating real-world efficacy and translational potential.
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