Saralasin TFA – Purity 99.65% | GMP Manufacturer

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Saralasin TFA – Purity 99.65% | GMP Manufacturer

Original price was: $43.00.Current price is: $40.00.

Saralasin (TFA) is a synthetic angiotensin II analog supplied as high-purity lyophilized powder for research use. It is widely studied as a competitive angiotensin II receptor antagonist in cardiovascular and renin–angiotensin system research.

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Description

Product Description

Saralasin is a synthetic peptide analog of angiotensin II, modified to act as a competitive antagonist at angiotensin II receptors. Supplied as the trifluoroacetate (TFA) salt in lyophilized powder form, Saralasin is intended strictly for research and laboratory use.

Historically, Saralasin has played an important role in cardiovascular and endocrine research, particularly in studies of the renin–angiotensin–aldosterone system (RAAS). In experimental models, it is used to investigate angiotensin II–mediated vasoconstriction, blood pressure regulation, receptor binding dynamics, and hormone signaling pathways. Its well-characterized pharmacological profile makes it a classical reference compound in angiotensin receptor research.


Product Specifications

ItemDescription
Product NameSaralasin
SynonymsSaralasin Acetate, Angiotensin II Antagonist
CAS Number34273-10-4
Molecular FormulaC50H71N13O12 (peptide, approximate)
Molecular Weight~912.1 g/mol
Amino Acid SequenceSar¹-Ala⁸-Angiotensin II
Peptide TypeSynthetic angiotensin II analog peptide
FormLyophilized powder (TFA salt)
Purity≥98% (HPLC)
Strength Options1 mg / 5 mg / 10 mg
AppearanceWhite to off-white powder
Identity VerificationHPLC, Mass Spectrometry
SolubilitySoluble in water or aqueous buffers
PackagingSterile, sealed research vials
Storage Condition−20 °C, dry and light-protected
Intended UseResearch use only (RUO)

Applications

Saralasin is commonly used in the following research areas:

  • Renin–angiotensin–aldosterone system (RAAS) studies

  • Angiotensin II receptor binding and antagonism research

  • Cardiovascular physiology and blood pressure regulation models

  • Endocrine signaling and hormone interaction studies

  • Pharmacological comparison of angiotensin receptor modulators

  • PubMed – Use of an angiotensin II antagonist (saralasin) in the recognition of “angiotensinogenic” hypertension

    saralasin tfa Chemical structure
    saralasin tfa Chemical structure


Usage & Reconstitution

Saralasin (TFA) lyophilized powder should be handled using standard sterile laboratory techniques. Reconstitution is typically performed in sterile water or suitable aqueous buffers to prepare stock solutions for experimental use.

Aliquoting after reconstitution is recommended to avoid repeated freeze–thaw cycles. Final working concentrations should be optimized according to receptor assays and model systems.


Storage & Stability

  • Store unopened vials at −20 °C

  • Protect from moisture and light

  • Avoid repeated freeze–thaw cycles after reconstitution

  • Properly stored aliquots remain stable for extended research use


Shipping Guarantee

Saralasin (TFA) lyophilized powder is packaged according to standardized laboratory material handling procedures:

  • Moisture- and light-protected inner packaging

  • Secure outer containers for transit protection

  • Batch-level labeling for traceability

  • Cold-chain handling applied when required


Contact & Bulk Inquiry

For inquiries regarding Saralasin (TFA) high-purity lyophilized powder, including bulk supply, specifications, and research support, please contact our team through the inquiry form or designated communication channels.

Our team can assist with:

  • Bulk and wholesale supply options

  • Available specifications and batch consistency

  • Technical documentation requests (COA, HPLC, MS)

  • International shipping and logistics coordination


    Disclaimer

    This product is intended for research and laboratory use only.
    Not for human or veterinary use.
    All handling and experimental applications must comply with applicable laws and institutional regulations.

    Additional information

    Weight0.6 kg
    Dimensions36 × 32 × 36 cm

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    1. What is Saralasin mainly used for in research?

    It is primarily used to study angiotensin II receptor antagonism and RAAS signaling.

    2. How does Saralasin differ from angiotensin II?

    It is a modified analog designed to competitively inhibit angiotensin II receptors.

    3. What purity level is provided?

    The peptide is supplied with ≥98% purity, verified by HPLC.

    4. How is product identity confirmed?

    Identity is confirmed using HPLC and mass spectrometry.

    5. How should Saralasin be reconstituted?

    It is typically reconstituted in sterile water or appropriate aqueous buffers.

    6. What storage conditions are recommended?

    Store at −20 °C, protected from light and moisture.

    7. Can Saralasin be used in cardiovascular research models?

    Yes, it is widely studied in experimental cardiovascular and endocrine models.

    8. Is this product intended for clinical use?

    No. It is strictly intended for research and laboratory use only.

    9. What factors should be considered in experimental design?

    Receptor expression, peptide concentration, and assay conditions.

    10. Is bulk supply available for research institutions?

    Yes, multiple package sizes are available to support bulk research requirements.


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