Description
HLF1-11, also known as Human Lactoferrin Peptide 1-11, is a synthetically derived peptide from the N-terminus of lactoferrin. This antimicrobial agent demonstrates broad-spectrum activity, including inhibition of human MPO activity and modulation of immune responses such as directing monocyte differentiation toward macrophages. Its synthetic nature ensures high batch consistency and purity. Manufactured under GMP protocols, this product is ideal for microbiology, immunology, and antimicrobial mechanism studies. For laboratory research use only.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | HLF1-11 (Human Lactoferrin Peptide 1-11) |
| Synonyms | HLF(1-11); N-terminal Human Lactoferrin Peptide |
| CAS No. | 183623-03-2 |
| Peptide Sequence | GRRRRSVQWCA |
| Molecular Formula | C??H??N??O??S |
| Molecular Weight | ~1374.58 Da |
| Purity | ?99.91% (GMP-quality) |
| Appearance | White to off-white solid powder |
| Solubility | Soluble in DMSO and aqueous buffers |
| Storage | Store lyophilized at –20 °C, dry, and protected from light |
| Manufacturer Standard | GMP-compliant production |
| Applications | Antimicrobial studies, immune modulation assays, monocyte/macrophage differentiation models |
| Regulatory Status | For laboratory research use only |
Mechanism of Action & Research Applications
HLF1-11 functions as an antimicrobial peptide derived from lactoferrin’s N-terminal region. It inhibits human MPO activity and influences immune functionality by directing GM-CSF-driven monocyte differentiation toward macrophages, thereby enhancing immune responses. Ideal for studies of host defense mechanisms, antimicrobial pathways, and immunomodulation in cellular or microbial research systems. For laboratory research use only.
Side Effects (For Reference Only in Models)
In experimental models, HLF1-11 may impact immune cell viability or differentiation patterns. Cellular assays may show altered cytokine profiles or phagocytic activity. These observations are for modeling purposes only and do not predict clinical safety. For laboratory research use only.
Disclaimer
HLF1-11 is intended strictly for laboratory research use only. It is not approved for human or veterinary use. Handling should follow institutional safety protocols.


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