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Talfirastide Acetate (CAS 2855063-75-9) – GMP-Manufacturer
$2.00
Talfirastide Acetate, also known as Angiotensin 1-7 Acetate, is a synthetic RAS-derived heptapeptide (DRVYIHP-acetate) with ?99.87% purity, produced in a GMP-compliant facility. Demonstrates anti-fibrotic, anti-angiogenic, and ACE-inhibitory properties. Designed exclusively for laboratory research use.?For wholesale prices, other specifications and uses, please consult our staff?
Description
Talfirastide Acetate (Ang-(1-7) Acetate) is a synthetic heptapeptide derived from the renin–angiotensin system. It exerts cardioprotective effects through ACE inhibition, modulation of kinin-induced vasodilation, and anti-inflammatory actions. Research shows it can inhibit tumor cell growth, reduce angiogenesis, and protect against vascular smooth muscle proliferation. Manufactured under GMP conditions with ?99.87% purity, this peptide is ideal for cardiovascular, inflammatory, and angiotensin-related signal pathway studies. For laboratory research use only.
Talfirastide Acetate Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Talfirastide Acetate |
| Synonyms | Ang-(1-7) Acetate; TXA127 Acetate |
| CAS No. | 2855063-75-9 |
| Sequence | Asp-Arg-Val-Tyr-Ile-His-Pro + Acetate (DRVYIHP-acetate) |
| Molecular Formula | C??H??N??O??·C?H?O? |
| Molecular Weight | ~959.06 Da |
| Purity | ?99.87% (GMP-grade) |
| Appearance | White to off-white solid |
| Solubility | Highly soluble in water (e.g., 60 mg/mL) |
| Storage Conditions | Store at –20 °C, dry, protected from light |
| Manufacturing Standard | GMP-compliant facility |
| Research Applications | Cardiovascular protection; inflammation; ACE inhibition; angiogenesis; tumor growth models |
| Regulatory Status | For laboratory research use only |
Talfirastide Acetate Mechanism of Action & Research Applications
Talfirastide Acetate binds to ACE and inhibits its activity (IC?? ~0.65 µM), enhancing vasodilation via nitric oxide and kinin pathways. It counters Ang II-induced smooth muscle proliferation, suppresses endothelial angiogenesis, and exhibits antifibrotic and anti-inflammatory effects—especially in cardiovascular and colitis models. Valuable for research in RAS signaling, vascular biology, oncology, and inflammatory disease. For laboratory research use only.
Talfirastide Acetate Side Effects (For Reference Only in Models)
In experimental models, high doses may influence blood pressure or vascular tone, and local tissue effects may occur. Observations are context-dependent and for experimental design only. For laboratory research use only.
Disclaimer
Talfirastide Acetate is intended strictly for laboratory research use only. It is not approved for human or veterinary use. Handling should comply with institutional safety guidelines.
Additional information
| Weight | 1 kg |
|---|---|
| Dimensions | 26 × 23 × 26 cm |
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