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BIO-1211 (CAS 187735-94-0) – High Purity 99.81% – GMP Manufacturer
$2.00
BIO-1211 is a synthetic small molecule (99.81% purity) that functions as a potent and selective ?4?1 integrin (VLA-4) inhibitor. Manufactured under GMP standards, available for both wholesale and retail—strictly for laboratory research use only.?For wholesale prices, other specifications and uses, please consult our staff?
Description
BIO-1211 (CAS 187735-94-0) is a synthetic inhibitor targeting the integrin ?4?1 (VLA-4), demonstrating high affinity and selectivity for the activated form of the receptor. It exhibits an IC?? of approximately 4 nM for ?4?1 and about 2 µM for ?4?7, showing over 200-fold selectivity toward ?4?1. Purity is 99.81%, produced under GMP-compliant conditions to support research in immunology, inflammation, and cell adhesion. It’s intended strictly for laboratory research use only.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | BIO-1211 |
| CAS No. | 187735-94-0 |
| Purity | 99.81% |
| Molecular Formula | C??H??N?O? |
| Molecular Weight | ~708.81 Da (free base) |
| Sequence | MPUPA-LDVP (tetrapeptide-like motif) |
| Appearance | White to off-white powder |
| Solubility | Soluble in water (~2 mg/mL), compatible with DMSO |
| Storage Conditions | Store at –20 °C, protected from moisture and light |
| Manufacturing Standard | GMP-compliant |
| Applications | Research in integrin inhibition, immunology models, inflammation studies |
| Regulatory Status | For laboratory research use only |
Mechanism of Action & Research Applications
BIO-1211 selectively binds to and inhibits activated integrin ?4?1, playing a critical role in leukocyte recruitment and immune response modulation. It significantly reduces cell adhesion and migration in inflammatory models. Its high selectivity makes it a valuable tool for immunological, oncology, and cell adhesion research.
Disclaimer
This product is intended strictly for laboratory research use only. It is not approved for human or veterinary use. Please adhere to institutional safety protocols when handling.
Additional information
| Weight | 1 kg |
|---|---|
| Dimensions | 62 × 36 × 62 cm |
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