Description

Product Description

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrial-encoded peptide discovered as part of a group of mitochondrial-derived peptides (MDPs) that participate in cellular metabolic regulation and stress response pathways. Unlike most peptides encoded by nuclear DNA, MOTS-c originates from the mitochondrial genome and has been shown to influence cellular energy metabolism and adaptive stress signaling.

In experimental research,  is widely investigated for its role in regulating glucose metabolism, insulin sensitivity, and mitochondrial-to-nuclear communication. Studies have demonstrated that MOTS-c can translocate to the nucleus under metabolic stress conditions and regulate gene expression associated with metabolic adaptation.

Because of these properties, MOTS-c has become an important research peptide in fields such as mitochondrial biology, metabolic disease modeling, aging research, and exercise physiology.

Product Specifications

Applications

MOTS-c peptide is widely used in multiple research areas:

• Mitochondrial signaling and mitochondrial-nuclear communication studies

• Metabolic regulation and glucose homeostasis research

• Insulin sensitivity and metabolic disease models

• Cellular stress response and metabolic adaptation studies

• Aging and longevity research models

Usage & Reconstitution

MOTS-c lyophilized peptide should be handled using standard sterile laboratory techniques. Reconstitution is typically performed using sterile water or suitable buffered solutions to prepare concentrated stock solutions.

After reconstitution, aliquoting is recommended to minimize repeated freeze–thaw cycles. Experimental concentrations should be optimized based on the specific biological model or assay system.

Storage & Stability

• Store unopened vials at −20 °C

• Protect from moisture and direct light

• Avoid repeated freeze–thaw cycles

• Reconstituted solutions should be aliquoted and stored appropriately

Shipping Guarantee

MOTS-c peptide is packaged following standardized research material shipping procedures:

• Moisture-proof and light-protected inner packaging

• Secure outer containers to prevent transit damage

• Batch labeling for traceability

• Temperature-controlled logistics when required

Contact & Bulk Inquiry

For inquiries regarding MOTS-c Peptide high-purity lyophilized powder, including bulk supply, specifications, and research documentation, please contact our team through the inquiry form or designated communication channels.

Our support team can assist with:

• Bulk and wholesale purchasing options

• Available strengths and batch consistency

• Technical documentation requests (COA, HPLC, MS)

• International shipping and logistics coordination

Disclaimer

This product is intended for research and laboratory use only.
Not for human or veterinary use.
All experimental applications must comply with applicable regulations and institutional policies.